Glyxambi
Home About us Editorial board Ahead of print Current issue Search Archives Submit article Instructions Subscribe Contacts Login 
  • Users Online: 1117
  • Home
  • Print this page
  • Email this page

   Table of Contents      
ARTICLES
Year : 1974  |  Volume : 22  |  Issue : 3  |  Page : 20-21

Intraocular metastasis in primary breast cancer


L. L. R. M. Medical College, Meerut, India

Correspondence Address:
I N Raizada
L. L. R. M. Medical College, Meerut
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


PMID: 4465289

Rights and PermissionsRights and Permissions

How to cite this article:
Raizada I N. Intraocular metastasis in primary breast cancer. Indian J Ophthalmol 1974;22:20-1

How to cite this URL:
Raizada I N. Intraocular metastasis in primary breast cancer. Indian J Ophthalmol [serial online] 1974 [cited 2019 Dec 14];22:20-1. Available from: http://www.ijo.in/text.asp?1974/22/3/20/31360

Secondary choroidal deposits from primary tumours in other parts of the body are rare. A case of choroidal metastasis from a breast carcinoma is being presented due to its rarity.


  Case Report Top


K.W. a woman of 48 years, in menopause, using presbyopic glasses attended the department of ophthal­mology, L. L. R. M. Medical College, Meerut, with complaints of failing vision and dull pain in the right eye.

Ocular Examination : Vision the in right eye was counting fingers at one meter and left eye had vision of 6)9. Funduscopy showed a large, slightly raised yellowish grey area in the upper temporal quadrant in the right eye involving the macula. [Figure - 1] Intraocular tension and anterior segments in both eyes were normal.

General Examination : A small tumour was found in the upper inner quadrant of the right breast. Re­gional lymph nodes were enlarged. The patient was referred to the surgical side. A biopsy was done. Histologically, the tumour was poorly differentiated invasive carcinoma. [Figure - 2]

She had no neurological signs. She died after 7 months.


  Discussion Top


Retinal secondaries as a manifestation of generalised disease are rare. Pearls' for the :first time in 1872 reported secondaries in the eye from primary bronchogenic carcinoma.

Godtfredsen [4] reported an incidence of 0.7%. Albert [1] et al reported the incidence of metastsis in the eye or the orbit as 0.7%. Guthert [5] et al on autopsy examination of the eyes of proven systemic carcinoma, reported an inci­dence of 0.5%. Bloch and Gartner [2] found intraocular lesion in 12% of patients. In Moorefield Eye Hospital, from 1935 to 1953, 40 cases of metastatic carcinoma of the choroid were noted.

The incidence of secondaries in the eye in cases of generalised disease is low because of the anatomical relationship of the ophthalmic artery to the internal carotid artery. The oph­thalmic artery arises at right angle from the artery and the metastatic emboli tend to pass straight to the brain and the meninges instead of going into the eye. The left eye is mostly affected because the tumour emboli pass into the left common carotid artery directly from aorta[6].


  Conclusion Top


A case of retinal metastasis from primary breast cancer has been reported.

The interesting features of the case are (a) Initial visual presentation. (b) Involvement of the right eye. (c) No neurological symptoms.

 
  References Top

1.
Albert D. Rubenosteen, R. and Scheie, H., 1967 Amer. J. Ophthal. 63, 723.  Back to cited text no. 1
    
2.
Bloch, R.S. and Gartner, S., 1971 Arch Ophthal. 85,673.  Back to cited text no. 2
    
3.
Duke-Elder, Perkins, E.S., 1966 System of Oph­thalmology 9, 917 London Kimpton.  Back to cited text no. 3
    
4.
Godtfredsen, E., 1944 Acta Ophthal 22, 394.  Back to cited text no. 4
    
5.
Gudhert, H., Janish, W. and Rossbach. K, 1965 Munch med schr 107, 939. cited by Bolus Jour­nal of R.C.S., Edinburgh 18, 1973.  Back to cited text no. 5
    
6.
Pearls, M. (1972 Vircows Arch Path Anat. Physiol 56, 445. Quoted by Duke Elder, Vol. IX.  Back to cited text no. 6
    


    Figures

  [Figure - 1], [Figure - 2]



 

Top
 
 
  Search
 
    Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
    Access Statistics
    Email Alert *
    Add to My List *
* Registration required (free)  

 
  In this article
Case Report
Discussion
Conclusion
References
Article Figures

 Article Access Statistics
    Viewed1250    
    Printed32    
    Emailed0    
    PDF Downloaded0    
    Comments [Add]    

Recommend this journal