Home About us Editorial board Ahead of print Current issue Search Archives Submit article Instructions Subscribe Contacts Login 
  • Users Online: 3581
  • Home
  • Print this page
  • Email this page

   Table of Contents      
ARTICLES
Year : 1983  |  Volume : 31  |  Issue : 7  |  Page : 964-965

Heredity in lattice degeneration of the retina


A.M. U Institute of Ophthalmology, Aligarh, India

Correspondence Address:
Manoj Shukla
A.M. U Institute of Ophthalmology, Aligarh
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


PMID: 6544299

Rights and PermissionsRights and Permissions

How to cite this article:
Shukla M, Ahuja O P. Heredity in lattice degeneration of the retina. Indian J Ophthalmol 1983;31, Suppl S1:964-5

How to cite this URL:
Shukla M, Ahuja O P. Heredity in lattice degeneration of the retina. Indian J Ophthalmol [serial online] 1983 [cited 2020 May 27];31, Suppl S1:964-5. Available from: http://www.ijo.in/text.asp?1983/31/7/964/29718

Table 1

Click here to view
Table 1

Click here to view
Lattice degeneration of the retina is the most common cause of retinal detchment. In a previous study we described the possible role of certain hereditary factors in the etiopathogenesis of this condition.[1] The pre­sent study was undertaken to find out the association of heredity and lattice degenera­tion of the retina.


  Material and methods Top


78 family members of 19 subjects having lattice degeneration of the retina in different stages of its evolution [Table - 1] were examined after maximal dilatation of pupils by an indirect ophthalmoscope and scleral depressor. This was supplemented by pos­terior segment biomicroscopy with the help of a Goldmann's three mirror contact lens in eyes having lattice degeneration of the retina. The findings were recorded on a conventional fundus topography chart.


  Observations Top


Lattice degeneration of the retina was seen in family members of 9(47.37%) subjects out of 19 studied. A total of 38 family members of these 9 subjects were examined and lattice degeneration of the retina was seen in 16(42.11%) of them. 4 out of 19 subjects had extensive (360°) lattice degeneration. Interes­tingly one family member each of two of these subjects also had similar extensive lesions. Family members of another subject having extensive lattice lesions revealed isolated lesions while family members of fourth sub­ject did not reveal lattice lesions. Itwas further significant to observe that fifty percent or more family members of 4 subjects were affec­ted with lattice degeneration which was associated with partial thickness round holes in one family member each of two subjects.


  Discussion Top


Hereditary aspect of lattice degeneration of the retina has received comparatively lesser attention although clinical and his­topathclogical features of this condition have been comprehensively described. Gartner[2] described the familial occurence of lattice degeneration of the retina in non-myopic sub­jects, Everett[3] suggested an autosomal domi­nant mode of inheritance with incomplete penetrance. Lewkonia et a1[4] observed lattice degeneration in 6 (10%) members out of 59 examined in a family of 110 members. The present study durther highlights the role of hereditary factors in the development of lat­tice degeneration of the retina. In this regard, long term family studies will be extremely important to exactly define the hereditary status of lattice degeneration. It is strongly advocated that family members of subjects having lattice degeneration of the retina should be meticulously examined to detect similar lesions in their eyes. Such an approach would also help in formulating guidelines for the prophylactic treatment of this condition in the prevention of retinal detachment.


  Summary Top


78 family members of 19 subjects having lattice degeneration of the retina were examined to detect similar lesions in their eyes. Lattice degeneration was seen in 16 (42.11%) out of 38 family members of 9 sub­jects. It is believed that hereditary lat*ice degeneration is a specific disease process and as such long term family studies of subjects having lattice degeneration of the retina would be very informative specially with regards to prevention of retinal detachment caused by this condition.

 
  References Top

1.
Shukla, M. and Ahuja O.P., 1981, Amer, J. Ophthalmol. 92: 482  Back to cited text no. 1
    
2.
Gertner, J., 1960, Klin. Mbl. Augenh. 136: 523  Back to cited text no. 2
    
3.
Everett. E.G., 1968, Amer, J. Ophthalmol. 65: 229  Back to cited text no. 3
    
4.
Lewkonia, I. Davis, M.S. and Salmon, T.D., 1973, Brit. J. Ophthalmol. 57 566  Back to cited text no. 4
    



 
 
    Tables

  [Table - 1]



 

Top
 
 
  Search
 
    Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
    Access Statistics
    Email Alert *
    Add to My List *
* Registration required (free)  

 
  In this article
Material and methods
Observations
Discussion
Summary
References
Article Tables

 Article Access Statistics
    Viewed3020    
    Printed49    
    Emailed1    
    PDF Downloaded0    
    Comments [Add]    

Recommend this journal