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   Table of Contents      
ORIGINAL ARTICLE
Year : 1984  |  Volume : 32  |  Issue : 3  |  Page : 153-155

Prevalence of mycotic infections of external eye


Department of Microbiology, L. TM. Medical College, Sion, Mumbai, India

Correspondence Address:
Leena P Deodhar
Prof. & Head of Microbiology, L.T.M. Medical College, Sion, Mumbai 400 022
India
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Source of Support: None, Conflict of Interest: None


PMID: 6335130

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How to cite this article:
Mohanty P K, Ambekar V A, Deodhar LP. Prevalence of mycotic infections of external eye. Indian J Ophthalmol 1984;32:153-5

How to cite this URL:
Mohanty P K, Ambekar V A, Deodhar LP. Prevalence of mycotic infections of external eye. Indian J Ophthalmol [serial online] 1984 [cited 2020 Aug 6];32:153-5. Available from: http://www.ijo.in/text.asp?1984/32/3/153/27409



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The eye is continuously exposed to exter­nal environment which is full of bacteria, fungi and viruses. The infections of cornea, lid margin, lacrimal sac as well as ulcers of the cornea due to injury are common problems. A few predisposing factors such as increased use of antibiotics and steroids, chronic debilitating diseases, radiotherapy, exposure to x-rays etc. are known to increase the incidence of mycotic infections of the eye.

The present study was undertaken to study the incidence of mycotic infections as well as the normal fungal flora of external eye.


  Materials and methods Top


370 ophthalmic patients were studied. Nor­mal fungal flora was studied in 50 healthy individuals.

Material was collected with the help of two sterile conjunctival swabs, for preparation of smears and inoculation on culture medium. In cases of corneal ulcer and conjunctivitis, material was collected more than once, when patients visited out-patient department again.

Standard methods as described by Emmons[1] and Rippon[2] were used for isola­tion and identification of different fungi.


  Observations Top


Out of 50 healthy individuals two showed presence of fungus in their conjunctiva.

In forty five patients fungi were consid­ered pathogenic, as they were isolated more than once [Table - 1]. Twelve patients were receiving local and/or systemic antibiotic treatment and 20 patients were on combined treatment of antibiotics and steroids.

The incidence of oculomycosis was highest in patients with corneal ulcer (6.75%) as compared to blepharitis, chronic dacryocystitis and post operative conditions.

45 strains of fungi were isolated from 45 patients. No patient showed infection due to more than one species. The most common isolate was the fungus Aspergillus [Table - 2]. [Table - 3] shows the distribution of fungal isolates in different clinical conditions.


  Discussion Top


Predominant fungi which constitute the normal fungal, flora of external eye are Aspergillus, Rhadotorula, Candida and Penicillium.[5],[6],[7]

In the present study out of 50 healthy per­sons, only two persons (4%) showed presence of fungus in their conjunctiva. This incidence is slightly lower as compared to other Indian workers.[4] The fungi isolated from normal individuals were Aspergillus fumigatus and candida albicans.

Out of 370 patients, fungi were isolated more than once from external ocular lesions of 45 (12.2%) patients while other inves­tigators[5],[7]],[8] have reported a lower incidence than this. The predominant isolate was fungus Aspergillus (57.7%) followed by dif­ferent species of Candida (35.5%).

22 patients of corneal ulcer out of a total of 25 were receiving either antibiotics alone or combined treatment of antibiotics and steroids. This treatment might have resulted in mycotic infection. The possible role of antibiotics and corticosteroids in oculo­mycosis has been emphasised by various workers.[3]

From a single case of orbital cellulitis, mucor was isolated. The patient was 55 year old and was suffering from diabetes. Several workers have reported isolation of mucor from orbital cellulitis.[7],[9]


  Summary Top


In this study two healthy individuals out of 50, showed the presence of fungus in their conjunctiva, while in 45 patients with ophthalmic complaints (out of a total of 370 cases) different fungi were isolated, the pre­dominant isolate being Aspergillus. Majority of the patients were receiving antibiotics and/ or corticosteroids.


  Acknowledgements Top


We are grateful to the Dean, L.T.M.M. College for allowing us to publish this paper.

 
  References Top

1.
Emmons Chester, W., 1970., Medical Mycology, Lea and Febiger, Philadelphia, pp 167.  Back to cited text no. 1
    
2.
Rippon J.W., 1974, Medical Mycology, W.B. Saun­ders Company, Philadelphia, pp. 217.  Back to cited text no. 2
    
3.
Agarwal L.P., and Kosla P.K., 1963, Orient Arch.Ophthalmol. 1: 45.  Back to cited text no. 3
    
4.
Edward S. Merck, 1974, Current concepts in Ophthalmology, Vol. IV, C.V. Mosby Co. Saint Luis, pp 215.  Back to cited text no. 4
    
5.
Frederick C. Blottic, 1974, Current concepts in Ophthalmology, Vol. IV, C.V. Mosby Co. Saint Luis.  Back to cited text no. 5
    
6.
Helde C., and Okumoto M., 1966, Cited by Locatcher Khorazo.  Back to cited text no. 6
    
7.
Janke and Schwab, 1961. Cited by Locatcher Khorazo.  Back to cited text no. 7
    
8.
Locatcher Khorazo and seegal, B.C. 1972, Mic­robiology of eye. C.V. Mosby Co. Saint Luis, pp 211.  Back to cited text no. 8
    
9.
Wilson LA., Ahern D.G., Jones D.B., and Sexton RR, 1969. Am. J. Ophthalmol. 52:127.  Back to cited text no. 9
    



 
 
    Tables

  [Table - 1], [Table - 2], [Table - 3]



 

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