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ORIGINAL ARTICLE
Year : 1991  |  Volume : 39  |  Issue : 1  |  Page : 22-24

Conjunctival impression cytology in dry eye states


Sarojini Devi Eye Hospital, Hyderabad-500 028, India

Correspondence Address:
S C Reddy
Sarojini Devi Eye Hospital, Hyderabad-500 028
India
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Source of Support: None, Conflict of Interest: None


PMID: 1894340

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Impression cytology technique was used to study the cytological changes of in 30 patients with various diseases (Xerophthalmia, Steven-Johnson's syndrome, trachoma, alkali burns, kerato conjunctivitis sicca) resulting in dry eye syndrome. The main features of impression cytology were squamous metaplasia of epithelial cells and altered goblet cell density. The comparison between conjunctival biopsy findings and impression cytology confirm that impression cytology provides the same information as that of biopsy. Hence, the authors advocate that this non-invasive simple technique can replace conjunctival biopsy in confirmation of diagnosis in dry eye syndrome.


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