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ORIGINAL ARTICLE
Year : 1991  |  Volume : 39  |  Issue : 2  |  Page : 44-47

Lactate dehydrogenase (LDH) isoenzymes patterns in ocular tumours


1 Department of Ophthalmology, Banaras Hindu University, Varanasi-221 005, India
2 Department of Pathology Institute of Medical Sciences, Banaras Hindu University, Varanasi-221005, India

Correspondence Address:
Rajendra Singh
Department of Ophthalmology, Banaras Hindu University, Varanasi-221 005
India
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Source of Support: None, Conflict of Interest: None


PMID: 1916977

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Estimation of lactate dehydrogenase (LDH) isoenzymes in the serum and aqueous humor was carried out in 15 cases of benign ocular tumour, 15 cases of malignant tumor and 15 normal cases. Cases of both sexes aged between 1 year and 75 years were included. LDH, isoenzymes specially LDH4 and LDH5 are higher and LDH1 and LDH2 lower in sera of patients with malignant tumor specially retinoblastoma as compared to benign tumor cases and control cases. LDH isoenzymes in aqueous humor are significantly higher and show a characteristic pattern in retinoblastoma cases, the concentration was presumably too low in the control, malignant tumor other than retinoblastoma and benign tumor cases as its fractionation was not possible.


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