Glyxambi
Home About us Editorial board Ahead of print Current issue Search Archives Submit article Instructions Subscribe Contacts Login 
  • Users Online: 1594
  • Home
  • Print this page
  • Email this page
ORIGINAL ARTICLE
Year : 1996  |  Volume : 44  |  Issue : 4  |  Page : 219-223

Graded corneal sensitivity for screening of diabetic retinopathy


Postgraduate Institute of Medical Education and Research, Chandigarh, India

Correspondence Address:
Jagjit S Saini
Department of Ophthalmology, Postgraduate Institute of Medical Education and Research, Chandigarh-160 012
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


PMID: 9251266

Rights and PermissionsRights and Permissions

Several alternative approaches to screen diabetics followed by referral of patients with retinopathy changes, are being investigated. The intent is to demonstrate usefulness of a cost effective, easy and valid screening test. We investigated in this report the efficacy of graded corneal sensitivity for screening presence of diabetic retinopathy. In 105 randomly chosen subjects with (70 subjects) and without (35 subjects) diabetes mellitus, corneal aesthesiometry and status of retinopathy was determined independently. Corneal sensitivity in subjects of diabetes mellitus without retinopathy (1.170.29 gm/mm[2]) was significantly different when compared to healthy controls (0.990.04 gm/mm[2]) (p<0.01). Also corneal sensitivity in eyes with any type of retinopathy was significantly worse (1.941.33 gm/mm[2]) when compared to eyes without retinopathy. At a cut off value of 1.20 gm/mm[2] the sensitivity and specificity of corneal hypoesthesia as a test to detect diabetic retinopathy was 86% and 74%, respectively. For detecting presence of proliferative diabetic retinopathy at a cut off value of 1.49 gm/mm[2] the sensitivity and specificity were 89% and 80% respectively. These observations indicate that corneal hypoesthesia may be a reasonable indication of the presence of diabetic retinopathy and could be used to screen diabetic populations for retinopathy, after its validity is confirmed in larger studies.


[FULL TEXT] [PDF Not available]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed3914    
    Printed164    
    Emailed8    
    PDF Downloaded10    
    Comments [Add]    

Recommend this journal