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ORIGINAL ARTICLE
Year : 2004  |  Volume : 52  |  Issue : 1  |  Page : 41-44

Clinical and histopathological characteristics of uveal melanoma in asian indians. A study of 103 patients


Sankara Nethralaya, Chennai, India

Correspondence Address:
J Biswas
Sankara Nethralaya, Chennai
India
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Source of Support: None, Conflict of Interest: None


PMID: 15132378

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Purpose: To study the clinical and histopathological characteristics of uveal melanomas in Asian Indians and compare them with other ethnic groups. Materials and Methods: One hundred and three enucleated eyes with clinical diagnosis of uveal melanoma were retrospectively studied (1987-2001) and the clinical and pathological features analysed. Results: Uveal melanomas constituted 0.02% of outpatients in a referral eye hospital in India over a 12-year period. The patients were predominantly males. Uveal melanomas tended to occur in the younger age. The mean age was 45.714.2 years. Melanoma involved the choroid in 90 (87.37%) patients, and both choroid and ciliary body in 13 (12.62%) patients. Mean basal diameter of the tumour was 13.435.32 mm. Mixed cell type was more common. Conclusion: Uveal melanomas are rare in the Asian Indians compared to those in the West. They occur in younger persons, have a greater mean basal diameter than that of Caucasians and are predominantly of the mixed cell type.


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