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   Table of Contents      
LETTER TO EDITOR
Year : 2004  |  Volume : 52  |  Issue : 3  |  Page : 262

Transpupillary thermotherapy for choroidal neovascular membrane in age related macular degeneration.


Correspondence Address:
P Roy


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Source of Support: None, Conflict of Interest: None


PMID: 15510478

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Keywords: Choroidal Neovascularization, etiology, therapy, Humans, Hyperthermia, Induced, methods, Macular Degeneration, complications, Pupil


How to cite this article:
Roy P. Transpupillary thermotherapy for choroidal neovascular membrane in age related macular degeneration. Indian J Ophthalmol 2004;52:262

How to cite this URL:
Roy P. Transpupillary thermotherapy for choroidal neovascular membrane in age related macular degeneration. Indian J Ophthalmol [serial online] 2004 [cited 2019 Dec 11];52:262. Available from: http://www.ijo.in/text.asp?2004/52/3/262/14571

Dear Editor,

I read with interest the article "Transpupillary thermotherapy for choroidal neovascular membrance in age-related macular degeneration" by Agarwal et al.[1] I wish to highlight the following points for clarification:

1. The visual acuity profile as depicted in the Table 1 of the article (p 46) is probably uncharacteristic of an ideal sample of such a study. No patient with visual acuity < 6/60 was included in the study. Let me refer the readers to comparable data from some other studies. The two pioneer studies in the West had 20.3% (deduced)[2] and 40%[3] patients with visual acuity <6/60 in their samples. In a companion article by Verma et al,[4] the pretreatment average visual acuity was 6/120, whereas in the study in question the same was approximately 6/30.32. Therefore evidently the study sample did not adequately represent the whole spectrum of those eligible and requiring treatment.

2. In a study on exudative age-related macular degeneration such as this, where the change of visual acuity from pretreatment to post-treatment is expected to be confined to a narrow range of spectrum (as, for example, 20/160 to 20/320 in the MPS Subfoveal New CNV Study,[5] or 20/400 to 20/320 in Verma et al,[4] utilisation of the ETDRS Visual Acuity Chart instead of Snellen's Acuity Chart could have been a better option for its ability to precisely document even a small change in visual acuity.



 
  References Top

1.
Agarwal M, Shanmugam MP, Gopal L, Shetty N, Bhende M, Gopal G, et al. Transpupillary thermotherapy for choroidal neovascular membrane in age-related macular degeneration. Indian J Ophthalmol 2004;52:45-49.  Back to cited text no. 1
    
2.
Newsom RSB, McAlister JC, Saeed M, McHugh JDA. Transpupillary thermotherapy (TTT) for the treatment of choroidal neovascularisation. Br J Ophthalmol 2001;85:173-78.  Back to cited text no. 2
    
3.
Reichel E, Berrocal AM, Ip Michael, Kroll AJ, Desai V, Duker JS, et al. Transpupillary thermotherapy of occult subfoveal choroidal neovascularisation in patients with age-related macular degeneration. Ophthalmology 1999;106:1908-14.  Back to cited text no. 3
    
4.
Verma L, Tewari HK, Nainiwal S, Ravindranathan J. Transpupillary thermotherapy in subfoveal choroidal neovascular membrane secondary to age-related macular degeneration. Indian J Ophthalmol 2004;52:35-40.  Back to cited text no. 4
[PUBMED]    
5.
Macular photocoagulation Study Group. Visual outcome after laser photocoagulation for subfoveal choroidal neovascularisation secondary to age-related macular degeneration. Arch Ophthalmol 1994;112:480-88.  Back to cited text no. 5
[PUBMED]    




 

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