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BRIEF REPORT
Year : 2007  |  Volume : 55  |  Issue : 6  |  Page : 475-477

Systemic chemotherapy and tamoxifen induced regression of choroidal metastasis from a breast carcinoma in a male


1 Department of Ophthalmic and Facial Plastic Surgery, Orbital Diseases and Ocular Oncology, Aditya Jyot Eye Hospital Pvt Ltd; Department of Ocular Oncology, Advanced Centre for Treatment, Research and Education in Cancer (ACTREC), Tata Memorial Centre, Mumbai, India
2 Department of Retina, Aditya Jyot Eye Hospital Pvt. Ltd, Mumbai, India
3 Department of Cornea and Anterior Segment, Aditya Jyot Eye Hospital Pvt. Ltd, Mumbai, India

Correspondence Address:
Debraj Shome
Department of Ophthalmic and Facial Plastic Surgery, Orbit and Ocular Oncology, Aditya Jyot Eye Hospital Pvt Ltd, Plot No 153, Road No 9, Major Parmeshwaran Road, Wadala, Mumbai - 400 031
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0301-4738.36491

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We report a case of a 55-year-old male patient with breast carcinoma, who developed choroidal metastasis. The patient had undergone mastectomy for carcinoma of right breast, five years ago. The patient was advised close follow-up for the left eye, as he was already on tamoxifen therapy (started a month ago) for spinal metastasis. On last follow-up, a year later, the choroidal lesion had completely scarred, with no recurrences. Systemic hormonal therapy like tamoxifen given for the breast primary and other systemic metastases may cause regression of the choroidal metastasis, thereby avoiding ocular radiotherapy. Medline search revealed only one published case of regression of choroidal metastasis from a male breast primary, on tamoxifen therapy.


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