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   Table of Contents      
Year : 2009  |  Volume : 57  |  Issue : 1  |  Page : 73

Authors' reply

Sri Sankardeva Nethralaya, Beltola, Guwahati - 781 028, Assam, India

Date of Web Publication12-Dec-2008

Correspondence Address:
Dipankar Das
Sri Sankaradeva Nethralaya, Beltola, Guwahati - 781 028, Assam
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0301-4738.44502

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How to cite this article:
Das D, Deka P, Bhattacharjee K, Das JK, Kuri G, Deka AC, Bhattacharjee H. Authors' reply. Indian J Ophthalmol 2009;57:73

How to cite this URL:
Das D, Deka P, Bhattacharjee K, Das JK, Kuri G, Deka AC, Bhattacharjee H. Authors' reply. Indian J Ophthalmol [serial online] 2009 [cited 2020 May 31];57:73. Available from: http://www.ijo.in/text.asp?2009/57/1/73/44502

Dear Editor,

We thank Pellicelli et al , [1] for his keen interest and comments on our article on ocular adnexal lymphoma (OAL) in northeast Indian population. [2]

We fully agree that primary extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue type (MALT) is the most frequent type of non-Hodgkin lymphoma arising from ocular adnexa in consideration of REAL classification as reported in the literature. [3]

Some infectious agents particularly Chlamydia psittaci contributing to lymhomagenesis have been considered targets for new therapeutic strategies. In some studies, Chlamydia psittaci DNA has been detected in 80% of OAL. [4] However, it should be kept in mind that there is possible geographic difference in the etiology of OAL. [5],[6]

We agree that we have not considered role of infections like Chlamydia and hepatiits C virus in our study but hope such information will be taken into account when we do future research on this topic.

The current study findings suggest that antibiotics have variable efficacy against OAL. Future prospective trials with standard clinical objective and laboratory criteria and a longer follow-up period would be necessary to evaluate the role of antibiotics in the treatment of OAL further. [7]

  References Top

Pellicelli A, Zoli V, Remotti D. Ocular adnexal lymphoma and infectious agents. Indian J Ophthalmol 2009;57:72-3.  Back to cited text no. 1
[PUBMED]  Medknow Journal  
Das D, Deka P, Bhattacharjee K, Das JK, Kuri G, Deka AC, Bhattacharjee H. Ocular adnexal lymphoma in northeast Indian population. Indian J Ophthalmol 2008;56:153-5.  Back to cited text no. 2
[PUBMED]  Medknow Journal  
Cahill M, Barnes C, Moriarty P, Daly P, Kennedy S. Ocular adnexal lymphoma-Comparison of MALT lymphoma with other hisological types. Br J Ophthalmol 1999;83:742-7.  Back to cited text no. 3
Ferreri AJ, Ponjoni M, Guidoboni M, DeConciliis C, Resti AG, Mazzi B, et al . Regression of Ocular adnexal lymphoma after Chlamydia psittaci eradicating antibiotic therapy. J Clin Oncol 2005;23:5007-73.  Back to cited text no. 4
Vargas RL, Fallone E, Felgar RE, Friedberg JW, Arbini AA, Andersen AA, et al . Is there an association between ocular adnexal lymphoma and infection with Chlamydia psitacci ? The University of Rochester experience. Leuk Res 2006;30:547-51.  Back to cited text no. 5
Zhang GS, Winter JN, Variakojis D, Reich S, Lissner GS, Bryar P, et al . Lack of an association between Chlamydia psitacci and ocular adnexal lymphoma. Leuk Lymph 2007;48:577-83.  Back to cited text no. 6
Husain A, Roberts D, Pro B, Mclaughlin P, Esmaeli B. Metaanalysis of association between Chlamydia psittaci and Ocular adnexal lymphoma and response of oclar adnexal lymphoma to antibiotics. Cancer 2007;110:809-15.  Back to cited text no. 7


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