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   Table of Contents      
LETTER TO EDITOR
Year : 2010  |  Volume : 58  |  Issue : 4  |  Page : 347-348

Authors' reply


1 Department of Ophthalmology, Santa Casa de São Paulo, São Paulo, Brazil
2 Department of Ophthalmology, Santa Casa de São Paulo, São Paulo, Brazil; and W.K. Kellogg Eye Center, University of Michigan, Ann Arbor, MI, U.S.A
3 Department of Microbiology, Santa Casa de São Paulo, São Paulo, Brazil
4 W.K. Kellogg Eye Center, University of Michigan, Ann Arbor, MI, U.S.A
5 Department of Ophthalmology, Santa Casa de São Paulo, São Paulo, Brazil; and Department of Ophthalmology, Keio University - School Medicine, Tokyo, Japan

Date of Web Publication7-Jun-2010

Correspondence Address:
Ivana L Romero
Rua Martinico Prado 284/ Room 54, São Paulo, SP, Brazil - 01224-010

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Source of Support: None, Conflict of Interest: None


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How to cite this article:
Romero IL, Malta JB, Silva CB, Mimica LM, Soong KH, Hida RY. Authors' reply. Indian J Ophthalmol 2010;58:347-8

How to cite this URL:
Romero IL, Malta JB, Silva CB, Mimica LM, Soong KH, Hida RY. Authors' reply. Indian J Ophthalmol [serial online] 2010 [cited 2024 Mar 19];58:347-8. Available from: https://journals.lww.com/ijo/pages/default.aspx/text.asp?2010/58/4/347/64134

Dear Editor,

We appreciate the opinions about our article [1] by Wiwanitkit. [2] The adhesives, mainly ethyl-cyanoacrylate, have been studied by our group in different features. [3],[4] Previously, we mentioned that "high temperatures related to exothermic reaction of ethyl-cyanoacrylate polymerization may possibly induce a temporary bactericidal effect" [ 3] like Dr Viroj Wiwanitkit cited very well in his letter to the editor. Other studies, however, suggest that the antimicrobial activity could be related to the degradation products. [5],[6] Formaldehyde, one of degradation products of cyanoacrylate, for example, destroys cell membranes by denaturing the membrane proteins. [7] Toxic degradation products of cyanoacrylate may further slow cell growth, damage its physiological needs, and change its cellular membrane structure by inhibiting a specific receptor. [8]

 
  References Top

1.
Romero IL, Malta JB, Silva CB, Mimica LM, Soong KH, Hida RY. Antibacterial properties of cyanoacrylate tissue adhesive: Does the polymerization reaction play a role?. Indian J Ophthalmol 2009;57:341-4.  Back to cited text no. 1
[PUBMED]  Medknow Journal  
2.
Wiwanitkit V. Cyanoacrylate tissue adhesive. Indian J Ophthalmol 2010;58:347.  Back to cited text no. 2
[PUBMED]  Medknow Journal  
3.
Romero IL, Paiato TP, Silva CB, Nigro JB, Malta S, Jenne Mimica LM, et al. Different application volumes of ethyl-cyanoacrylate tissue adhesive can change its antibacterial effects against ocular pathogens in vitro. Curr Eye Res 2008;33:813-8.  Back to cited text no. 3
[PUBMED]  [FULLTEXT]  
4.
Romero IL, Barreto C, Mimica LMJ, Hida RY. Antimicrobial influence of polymerization process and degradation products of ethyl-cyanoacrylate in vitro for microorganisms related to corneal infection. Assoc Res Vis Ophthalmol 2007;48:4748.  Back to cited text no. 4
    
5.
Refojo MF, Koliopoulos J. Adhesives in ophthalmology. Surv Ophthalmol 1971;15:217-36.  Back to cited text no. 5
    
6.
Trott AT. Cyanoacrylate tissue adhesives. An advance in wound care. JAMA 1997;277:1559-60.  Back to cited text no. 6
[PUBMED]    
7.
McDonnell G, Russell AD. Antiseptics and disinfectants: activity, action, and resistance. Clin Microbiol Rev 1999;12:147-79.  Back to cited text no. 7
[PUBMED]  [FULLTEXT]  
8.
Reyes GF, Corbett D, Benz FW, Doyle RJ. Acrylonitrile induces autolysis Bacillus subtilis. FEMS Microbiol Lett 2000;182:255-8.  Back to cited text no. 8
[PUBMED]    




 

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