|
|
LETTER TO EDITOR |
|
Year : 2010 | Volume
: 58
| Issue : 4 | Page : 347-348 |
|
Authors' reply
Ivana L Romero1, Joao B N S Malta2, Cely B Silva3, Lycia M J Mimica3, Kaz H Soong4, Richard Y Hida5
1 Department of Ophthalmology, Santa Casa de São Paulo, São Paulo, Brazil 2 Department of Ophthalmology, Santa Casa de São Paulo, São Paulo, Brazil; and W.K. Kellogg Eye Center, University of Michigan, Ann Arbor, MI, U.S.A 3 Department of Microbiology, Santa Casa de São Paulo, São Paulo, Brazil 4 W.K. Kellogg Eye Center, University of Michigan, Ann Arbor, MI, U.S.A 5 Department of Ophthalmology, Santa Casa de São Paulo, São Paulo, Brazil; and Department of Ophthalmology, Keio University - School Medicine, Tokyo, Japan
Date of Web Publication | 7-Jun-2010 |
Correspondence Address: Ivana L Romero Rua Martinico Prado 284/ Room 54, São Paulo, SP, Brazil - 01224-010
Source of Support: None, Conflict of Interest: None | Check |
How to cite this article: Romero IL, Malta JB, Silva CB, Mimica LM, Soong KH, Hida RY. Authors' reply. Indian J Ophthalmol 2010;58:347-8 |
Dear Editor,
We appreciate the opinions about our article [1] by Wiwanitkit. [2] The adhesives, mainly ethyl-cyanoacrylate, have been studied by our group in different features. [3],[4] Previously, we mentioned that "high temperatures related to exothermic reaction of ethyl-cyanoacrylate polymerization may possibly induce a temporary bactericidal effect" [ 3] like Dr Viroj Wiwanitkit cited very well in his letter to the editor. Other studies, however, suggest that the antimicrobial activity could be related to the degradation products. [5],[6] Formaldehyde, one of degradation products of cyanoacrylate, for example, destroys cell membranes by denaturing the membrane proteins. [7] Toxic degradation products of cyanoacrylate may further slow cell growth, damage its physiological needs, and change its cellular membrane structure by inhibiting a specific receptor. [8]
References | | |
1. | Romero IL, Malta JB, Silva CB, Mimica LM, Soong KH, Hida RY. Antibacterial properties of cyanoacrylate tissue adhesive: Does the polymerization reaction play a role?. Indian J Ophthalmol 2009;57:341-4. [ PUBMED] |
2. | Wiwanitkit V. Cyanoacrylate tissue adhesive. Indian J Ophthalmol 2010;58:347. [ PUBMED] |
3. | Romero IL, Paiato TP, Silva CB, Nigro JB, Malta S, Jenne Mimica LM, et al. Different application volumes of ethyl-cyanoacrylate tissue adhesive can change its antibacterial effects against ocular pathogens in vitro. Curr Eye Res 2008;33:813-8. [ PUBMED] [ FULLTEXT] |
4. | Romero IL, Barreto C, Mimica LMJ, Hida RY. Antimicrobial influence of polymerization process and degradation products of ethyl-cyanoacrylate in vitro for microorganisms related to corneal infection. Assoc Res Vis Ophthalmol 2007;48:4748. |
5. | Refojo MF, Koliopoulos J. Adhesives in ophthalmology. Surv Ophthalmol 1971;15:217-36. |
6. | Trott AT. Cyanoacrylate tissue adhesives. An advance in wound care. JAMA 1997;277:1559-60. [ PUBMED] |
7. | McDonnell G, Russell AD. Antiseptics and disinfectants: activity, action, and resistance. Clin Microbiol Rev 1999;12:147-79. [ PUBMED] [ FULLTEXT] |
8. | Reyes GF, Corbett D, Benz FW, Doyle RJ. Acrylonitrile induces autolysis Bacillus subtilis. FEMS Microbiol Lett 2000;182:255-8. [ PUBMED] |
|