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   Table of Contents      
Year : 2010  |  Volume : 58  |  Issue : 6  |  Page : 551

Authors' reply

1 Department of Ophthalmology, Government Medical College, Aurangabad - 431 001, India
2 Department of Pathology, Government Medical College, Aurangabad - 431 001, India

Date of Web Publication16-Oct-2010

Correspondence Address:
Varsha Nandedkar
Associate Professor and Head of Unit Ophthalmology, Government Medical College, Aurangabad - 431 001
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Source of Support: None, Conflict of Interest: None

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How to cite this article:
Nandedkar V, Joshi AR, Kabra N, Deshpande NN. Authors' reply. Indian J Ophthalmol 2010;58:551

How to cite this URL:
Nandedkar V, Joshi AR, Kabra N, Deshpande NN. Authors' reply. Indian J Ophthalmol [serial online] 2010 [cited 2020 Jun 2];58:551. Available from: http://www.ijo.in/text.asp?2010/58/6/551/71687

Dear Editor,

First, we appreciate the details with which Chalisgaonkar et al. [1] have read our case report [2] and searched the literature of retinoblasotoma in adults.

In the case report by Biswas et al., [3] on the computed tomogram (CT), 'a speck of calcification' was noted. No gross calcified areas were found. In the remaining cases no calcification was noted.

In all case reports of retinoblastoma in adults, retinocytoma was diagnosed as benign appearing areas in malignant tumor tissue and not as pre-existing lesions that turned malignant on follow-up. [4] In our case no such benign appearing cells were noted in the malignant tissue, in the multiple tissue sections that were taken. [1]

Ours is the only case reported in literature where retinoblastoma was found in pregnancy. There is one case reported by Takahashi et al., [5] six months postpartum. We have stated that new cases and further study is needed for establishing this relationship. Pregnancy may have an effect on retinoblastoma due to circulating mutagens and immunosuppression. [6]

  References Top

Chalisgoankar C, Rathore MK, Dwivedi PK, Choudhay P, Lakhtakia S, Sharma K. Retinoblastoma in Pregnancy. Indian J Ophthalmol 2010;58:550.  Back to cited text no. 1
Nandedkar VS, Joshi AR, Kabra N, Deshpande NN. Presentation of retinoblastoma in pregnancy. Indian J Ophthalmol 2010;58:229-32  Back to cited text no. 2
Biswas J, Mani B, Shanmugan MP, Patwardhan D, Kumar KS, Badrinath SS. Retinoblastoma in adults: Report of three cases and review of literature. Surv Ophthalmol 2000;44:409-14.  Back to cited text no. 3
Odashiro AN, Pereira PR, de Souza Filho JP, Cruess SR, Burnier MN Jr. Retinoblastoma in an adult: Case report and literature review. Can J Ophthalmol 2005;40:188-91.  Back to cited text no. 4
Takahashi T, Tamura S, Inoue M, Isayama Y, Sashikata T. Retinoblastoma in a 26-year-old adult. Ophthalmology 1983;90:179-83.   Back to cited text no. 5
Antonelli NM, Dotters DJ, Katz VL, Kuller JA. Cancer in pregnancy: A review of literature. Obstet Gynecol Surv 1996;51:125-34.  Back to cited text no. 6


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