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LETTER TO THE EDITOR |
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| Year : 2012 | Volume
: 60
| Issue : 2 | Page : 164 |
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DNA chip-assisted diagnosis for ocular toxoplasmosis: A comment
Viroj Wiwanitkit
Wiwanitkit House, Bangkhae, Bangkok, Thailand
| Date of Web Publication | 20-Mar-2012 |
Correspondence Address:
Viroj Wiwanitkit
Wiwanitkit House, Bangkhae, Bangkok 10160
Thailand
DOI: 10.4103/0301-4738.94071 PMID: 22446926
How to cite this article:
Wiwanitkit V. DNA chip-assisted diagnosis for ocular toxoplasmosis: A comment. Indian J Ophthalmol 2012;60:164 |
How to cite this URL:
Wiwanitkit V. DNA chip-assisted diagnosis for ocular toxoplasmosis: A comment. Indian J Ophthalmol [serial online] 2012 [cited 2013 Jun 20];60:164. Available from: http://www.ijo.in/text.asp?2012/60/2/164/94071 |
Dear Editor,
I read the recent publication on DNA chip-assisted diagnosis for ocular toxoplasmosis with a great interest. [1] I accept that this report might imply the usefulness of DNA-chip technology in diagnosis of toxoplasmosis. However, there are some concerns in laboratory medicine for this report. First, although Basu et al., mentioned that validation of the DNA chip was already done there is no data on its diagnostic properties (sensitivities, specificity, accuracy, predictive value, etc.). Second, although the use of DNA chip helps provide diagnosis on multiple foci at a single time it can increase the error in the diagnosis. [2] Finally, I would like to conclude that the complete data on the properties as well as cost effectiveness of the DNA-chip approach is still required before implementation of this test for routine usage.
 References | |  |
| 1. | Basu S, Sharma S, Kar S, Das T. DNA chip-assisted diagnosis of a previously unknown etiology of intermediate uveitis-Toxoplasma gondii. Indian J Ophthalmol 2010;58:535-7. 
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| 2. | Pounds SB. Estimation and control of multiple testing error rates for microarray studies. Brief Bioinform 2006;7:25-36.
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