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Year : 2012  |  Volume : 60  |  Issue : 4  |  Page : 315-317

Desferrioxamine-related ocular toxicity: A case report

Retinal Unit, Department of Ophthalmology and Visual Sciences, Royal Adelaide Hospital, South Australia

Correspondence Address:
Sumu Simon
Department of Ophthalmology and Visual Sciences, Royal Adelaide Hospital, North Terrace, Adelaide-5000
South Australia
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0301-4738.98714

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A 29-year-old lady receiving repeated blood transfusions for β thalassemia since childhood, presented with rapidly deteriorating symptoms of night blindness and peripheral visual field loss. She was recently commenced on high-dose intravenous desferrioxamine for reducing the systemic iron overload. Clinical and investigative findings were consistent with desferrioxamine-related pigmentary retinopathy and optic neuropathy. Recovery was partial following cessation of desferrioxamine. This report highlights the ocular side-effects of desferrioxamine mesylate and the need to be vigilant in patients on high doses of desferrioxamine.

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