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   Table of Contents      
BRIEF COMMUNICATION
Year : 2012  |  Volume : 60  |  Issue : 4  |  Page : 324-325

Spontaneous globe luxation associated with chronic obstructive pulmonary disease


Department of Ophthalmology, Mahatma Gandhi Medical College and Research Institute, Puducherry, India

Date of Submission09-Sep-2010
Date of Acceptance28-Dec-2010
Date of Web Publication19-Jul-2012

Correspondence Address:
M Ashok Kumar
Mahatma Gandhi Medical College and Research Institute, Pillayarkupam, Puducherry - 607402
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0301-4738.98720

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  Abstract 

Spontaneous globe luxation is a rarely reported condition which can lead to complications like optic neuropathy. Common causes are thyroid eye disease, shallow orbit and floppy eyelid syndrome. We report a case of spontaneous globe luxation with the onset and severity associated with chronic obstructive pulmonary disease (COPD). To our knowledge, this is the first case of spontaneous globe luxation associated with COPD.

Keywords: Chronic obstructive pulmonary disease, globe luxation, spontaneous


How to cite this article:
Kumar M A, Srikanth K, Pandurangan R. Spontaneous globe luxation associated with chronic obstructive pulmonary disease. Indian J Ophthalmol 2012;60:324-5

How to cite this URL:
Kumar M A, Srikanth K, Pandurangan R. Spontaneous globe luxation associated with chronic obstructive pulmonary disease. Indian J Ophthalmol [serial online] 2012 [cited 2019 Jun 25];60:324-5. Available from: http://www.ijo.in/text.asp?2012/60/4/324/98720

Globe luxation occurs when the globe is displaced anteriorly beyond the orbital rim with retraction of the eyelids behind the globe and tethering of the optic nerve. [1] The resultant acutely occurring extreme proptosis can cause severe anxiety, pain, corneal exposure, retinal venous congestion and optic neuropathy. [2] Globe luxation can be spontaneous, traumatic or voluntary. We report a case of spontaneous globe luxation associated with chronic obstructive pulmonary disease (COPD). To our knowledge this is the first case report of such an association.


  Case Report Top


A 46-year-old male had been admitted in the intensive care unit (ICU) for severe chronic obstructive pulmonary disease (COPD; bronchial asthma). Patient developed acute proptosis of both eyes after admission. Based on the clinical picture of acute bilateral proptosis with retracted lids [Figure 1] and patient's history of similar episode in the past, a diagnosis of globe luxation was made and the globe was reduced by pressing on the superior sclera down and back while pinching the upper lid [Figure 2] and [Figure 3]. History from the patient and his wife revealed that he had previous such episodes over past 4-5 years. The episodes initiated after he started developing wheezing episodes and most of the globe luxation episodes occurred along with exacerbations of COPD. Ocular examination revealed bilateral pseudophakia with normal pupil and fundus. Axial length in both eyes was 23.8 mm. Computed tomography (CT) scan of orbit revealed no orbital mass [Figure 4]. CT scan showed a proptosed eye with a stretched optic nerve because patient developed luxation while CT was being performed. Orbit volume and globe volume appeared normal.
Figure 1: Prominent luxation of both globes

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Figure 2: Left globe has been reduced. Right eye still luxated

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Figure 3: Both globes have been reduced

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Figure 4: CT scan showing bilateral prominent globe luxation with stretched optic nerve

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During his stay in ICU, the patient had repeated episodes of globe luxation (almost every 2 hours) which was reduced each time. Bilateral temporary tarsorrhaphy was done after five to six episodes of repeated globe luxation to prevent the repeated proptosis. Unfortunately, the patient developed complications such as respiratory paralysis and septicemia and expired on the third day of admission.


  Discussion Top


Spontaneous globe luxation is a rare event. Kunesh et al. reviewed and found 26 reported cases of spontaneous globe luxation till 2001. [3] After that, another four case reports regarding spontaneous globe luxation could be identified in literature review till 2010. Spontaneous globe luxation occurs in patients with thyroid eye disease, [1] proptosis, floppy eyelid syndrome and shallow orbit. [4] Rare causes like histiocytosis X [5] and Engelmann's disease [6] have also been reported. Luxation can be precipitated by lid manipulation, Valsalva maneuver, trauma, general anesthesia [2] and even by contact lens insertion. [3] Structural anomalies resulting in laxity of orbital ligaments and extraocular muscles can predispose to globe luxation. Once the luxation starts, the orbicularis muscle goes into spasm to maintain the state of luxation.

The case reported here had a history of globe luxation whose onset correlated with increased severity of COPD. He also had recurrent luxation after admission for severe COPD. The raised intrathoracic pressure with resultant increased intraorbital pressure must have caused the luxation. Preexistent weaknesses of extraocular muscles and ligaments could have predisposed the patient for globe luxation. Floppy eyelid was not demonstrated in this patient. CT scan ruled out a shallow orbit or orbital mass as cause. Review of literature did not reveal any such case of luxation being precipitated and aggravated by COPD.

Management consists of simple reducing maneuvers like asking the patient to look down, pinching the upper lid and pressing on the superior sclera down and back. [1] This simple technique can be taught to the patient also and can help to avoid severe anxiety when the patient develops such an episode where help may not be available.

Surgical treatment consists of lateral tarsorrhaphy, pentagonal wedge eyelid resection and advancement of orbital wall. [4] But lateral tarsorrhaphy has also been reported to increase the risk of luxation by producing a tighter orbit and increased intraorbital pressure, and once luxation occurs, the smaller remaining palpebral aperture can hinder the reduction of the globe. [5]

 
  References Top

1.
Tse DT. A simple maneuver to reposit a subluxed globe. Arch Ophthalmol 2000;118:410-1.  Back to cited text no. 1
[PUBMED]    
2.
Clendenen SR, Kostick DA. Ocular globe luxation under general anaesthesia. Anesth Analg 2008;107:1630-1.  Back to cited text no. 2
[PUBMED]    
3.
Kunesh JC, Katz SE. Spontaneous globe luxation associated with contact lens placement. CLAO J 2002;28:2-4.  Back to cited text no. 3
[PUBMED]    
4.
Alexandrakis G, Tse DT, Chang WJ. Spontaneous globe luxation associated with Floppy eyelid syndrome and shallow orbits. Arch Ophthalmol 1999;117:138-9.  Back to cited text no. 4
[PUBMED]    
5.
Wood CM, Pearson AD, Craft AW, Howe JW. Globe luxation in histiocytosis X. Br J Ophthalmol 1988;72:631-3.  Back to cited text no. 5
[PUBMED]    
6.
Brodrick JD. Luxation of the globe in Englemann's disease. Am J Ophthalmol 1977;83:870-3.  Back to cited text no. 6
[PUBMED]    


    Figures

  [Figure 1], [Figure 2], [Figure 3], [Figure 4]



 

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