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BRIEF COMMUNICATION
Year : 2013  |  Volume : 61  |  Issue : 11  |  Page : 676-678

Delayed diagnosis of ocular syphilis that manifested as retinal vasculitis and acute posterior multifocal placoid epitheliopathy


Department of Ophthalmology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea

Correspondence Address:
Young Hee Yoon
Department of Ophthalmology, University of Ulsan College of Medicine, Asan Medical Center, #388-1 Pungnap2-Dong, Songpa-Gu, Seoul, 138-040
Korea
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0301-4738.119415

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A 55-year-old female presented with bilateral progressive retinal vasculitis. She was on systemic and intravitreal steroids on the basis of uveitis work-up result (negative result including rapid plasma reagin), but her visual acuity continued to deteriorate to light perception only. Ocular examination showed retinal vasculitis, multiple yellow placoid lesions and severe macula edema in both eyes. Repeated work-up revealed positivity of fluorescent treponemal antibody-absorption in serum and subsequently in cerebrospinal fluid. Ocular syphilis was diagnosed. And intravenous penicillin G resulted in rapid resolution of vasculitis and macular edema. To avoid delay in the diagnosis of ocular syphilis, high index of suspicion and repeating serological tests (including both treponemal and non-treponemal tests) are warranted.


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