Glyxambi
Home About us Editorial board Ahead of print Current issue Search Archives Submit article Instructions Subscribe Contacts Login 
  • Users Online: 4754
  • Home
  • Print this page
  • Email this page


 
   Table of Contents      
LETTER TO THE EDITOR
Year : 2013  |  Volume : 61  |  Issue : 11  |  Page : 685

The neutrophil lymphocyte ratio may be useful inflammatory indicator before applying other expensive and invasive procedures


1 Department of Cardiology, Gulhane Medical Academy Ankara, Ankara, Turkey
2 Department of Cardiology, Van Education and Research Hospital, Van, Turkey
3 Department of Internal Medicine, Gulhane Medical Academy Ankara, Ankara, Turkey

Date of Web Publication16-Dec-2013

Correspondence Address:
Sevket Balta
Department of Cardiology, Gulhane School of Medicine, Tevfik Saglam St., 06018 Etlik-Ankara
Turkey
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0301-4738.123150

Rights and Permissions

How to cite this article:
Demirkol S, Balta S, Kucuk U, Kucuk HO, Kurt O, Sarlak H. The neutrophil lymphocyte ratio may be useful inflammatory indicator before applying other expensive and invasive procedures. Indian J Ophthalmol 2013;61:685

How to cite this URL:
Demirkol S, Balta S, Kucuk U, Kucuk HO, Kurt O, Sarlak H. The neutrophil lymphocyte ratio may be useful inflammatory indicator before applying other expensive and invasive procedures. Indian J Ophthalmol [serial online] 2013 [cited 2019 Oct 16];61:685. Available from: http://www.ijo.in/text.asp?2013/61/11/685/123150

Dear Editor,

We read with interest article the entitled "Relation between platelet indices and branch retinal vein occlusion (BRVO) in hypertensive patients" by Onder et al.[1] They aimed to evaluate MPV in BRVO. They reported that MPV was significantly higher in patients with BRVO. The ready availability of MPV measurements at no additional cost may encourage its wider use in clinical practice.

Retinal vein occlusion is the most common retinal vascular occlusive disorder and is usually associated with a variable amount of loss of vision. Generally, branch retinal vein occlusion (BRVO) tends to be considered as one disease which is not only incorrect, but also cause of most of the confusion on the subject. A complete blood count is a relatively routine, inexpensive, practical, and easy examination that supplies additional information. MPV is a widely used laboratory marker associated with platelet function based on inflammatory conditions and thrombosis. [2] Recently, increased levels of MPV were demonstrated in cerebrovascular disease, peripheral artery disease, stroke, malignancy, gastrointestinal diseases, atrial fibrillation, [3] all of that are associated endothelial dysfunction on the basis of inflammation. [4] The higher MPV values are mentioned to be a beneficial marker of higher thromboycte activity and have been found to be associated with inflammation in patients with thyroid and rheumatic diseases. Platelet parameters might be influenced by coronary risk factors including age, obesity, smoking, diabetes mellitus, hypertension, hyperlipidemia, metabolic syndrome, and deep vein thrombosis. Furthermore, MPV value was found to be also higher in chronic obstructive pulmonary disease and nonalcoholic hepatic disease patients compared with a control group. Therefore, it may be interesting if the authors [1] provided information about these conditions.

Finally, not only MPV, but also red cell distribution width, neutrophil lymphocyte (N/L) ratio, [5] plateletcrit, platelet lymphocyte (P/L) ratio, C-reactive protein (CRP), gamma-glutamyl transferase (GGT), and uric acid are easy methods to evaluate the BRVO in hypertensive patients. These markers might be useful in clinical practice. We suggest that MPV ought to be evaluated together with other serum inflammatory markers such as N/L ratio, P/L ratio, GGT and uric acid.

 
  References Top

1.
Onder HI, Kilic AC, Kaya M, Bulur S, Onder E, Tunc M. Relation between platelet indices and branch retinal vein occlusion in hypertensive patients. Indian J Ophthalmol 2013;61:160-2.  Back to cited text no. 1
[PUBMED]  Medknow Journal  
2.
Balta S, Demirkol S, Celik T, Kucuk U, Unlu M, Arslan Z, et al. Association between coronary artery ectasia and neutrophil-Lymphocyte ratio. Angiology 2013;64:627-32.  Back to cited text no. 2
[PUBMED]    
3.
Balta S, Demirkol S, Kucuk U, Unlu M. Hemostatic markers can be pivotal roles of risk factors for new-onset atrial fibrillation. Platelets 2013. [In press].  Back to cited text no. 3
    
4.
Demirkol S, Balta S, Unlu M, Yuksel UC, Celik T, Arslan Z, et al. Evaluation of the mean platelet volume in patients with cardiac syndrome X. Clinics (São Paulo) 2012;67:1019-22.  Back to cited text no. 4
    
5.
Cingoz F, Iyisoy A, Demirkol S, Sahin MA, Balta S, Celik T, et al. Carotid intima-media thickness in patients with slow coronary flow and its association with neutrophil-to-lymphocyte ratio: A preliminary report. Clin Appl Thromb Hemost 2013. [In press].  Back to cited text no. 5
    




 

Top
 
 
  Search
 
    Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
    Access Statistics
    Email Alert *
    Add to My List *
* Registration required (free)  

 
  In this article
References

 Article Access Statistics
    Viewed597    
    Printed2    
    Emailed1    
    PDF Downloaded93    
    Comments [Add]    

Recommend this journal