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LETTER TO THE EDITOR
Year : 2013  |  Volume : 61  |  Issue : 2  |  Page : 86

Intravitreal ranibizumab for the treatment of choroidal neovascularization secondary to ocular toxoplasmosis


Department of Vitreo-Retina and Uvea, Aravind Eye Hospital, Hyderabad, India

Date of Web Publication15-Feb-2013

Correspondence Address:
Neeraj Pandey
Department of Vitreo-Retina and Uvea, Aravind Eye Hospital Pvt. Ltd. 12-2-824, Santosh Nagar Colony, Mehdipatnam, Hyderabad - 500 028
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0301-4738.107211

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How to cite this article:
Pandey N, Dwivedi V. Intravitreal ranibizumab for the treatment of choroidal neovascularization secondary to ocular toxoplasmosis. Indian J Ophthalmol 2013;61:86

How to cite this URL:
Pandey N, Dwivedi V. Intravitreal ranibizumab for the treatment of choroidal neovascularization secondary to ocular toxoplasmosis. Indian J Ophthalmol [serial online] 2013 [cited 2020 Mar 30];61:86. Available from: http://www.ijo.in/text.asp?2013/61/2/86/107211

Dear Editor,

We read the article by Shah et al. [1] with great interest. At first, we would like to congratulate the authors for a very nice case reported here. We have a few comments to make on this case report.

  1. Inflammatory choroidal neovascular membrane (CNVM) is not so uncommon to be seen as reported in the case and it may be associated with toxoplasmosis, tuberculosis, etc. [2],[3]
  2. Subretinal fluid (SRF) mentioned in [Figure 1] (color picture) is not very well supported by [Figure 2] where optical coherence tomography (OCT) does not show any SRF. Instead, it does show scarring.
  3. Blocked fluorescence seen in [Figure 2] may be due to the pigmentation around the lesion which may be a sign of longstanding lesion with retinal pigment epithelium (RPE) alteration.
  4. Hyperfluorescence seen in [Figure 2] may be staining of scar as it is a late phase angiogram picture. No early phase picture is shown in the support of early leak of CNVM.
  5. [Figure 3] is shown in the article as no leak with regressed CNVM, which is an early phase picture and it may take stain in late phase as in [Figure 2] if it was only scar. It is well supported by the OCT showing shadowing of the reflectivity behind the scar.
  6. Both the OCTs shown in [Figure 2] and [Figure 3] are probably not passing through the same place, so we cannot compare the reflectivity and shadowing of these two pictures.


 
  References Top

1.
Shah NJ, Shah UN. Intravitreal ranibizumab for the treatment of choroidal neovascularization secondary to ocular toxoplasmosis. Indian J Ophthalmol 2011;59:318-9.  Back to cited text no. 1
[PUBMED]  Medknow Journal  
2.
Adan A, Mateo C, Wolley-Dod C. Surgery for subfoveal choroidal neovascularization in toxoplasmic retinochoroiditis. Am J Ophthalmol 2003;135:386-7.  Back to cited text no. 2
    
3.
Chung YM, Yeh TS, Sheu SJ, Liu JH. Macular subretinal neovascularization in choroidal tuberculosis. Ann Ophthalmol 1989;21:225-9.  Back to cited text no. 3
[PUBMED]    




 

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