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Year : 2013  |  Volume : 61  |  Issue : 7  |  Page : 357-359

Distant metastatic retinoblastoma without central nervous system involvement

1 Ocular Oncology Service, L. V. Prasad Eye Institute, Road No. 2, Banjara Hills, Hyderabad, India
2 Apollo Cancer Hospital, Jubilee Hills, Hyderabad, India

Correspondence Address:
Santosh G Honavar
Ocular Oncology Service, L. V. Prasad Eye Institute, Road No. 2, Banjara Hills, Hyderabad - 500034
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0301-4738.97077

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Retinoblastoma is the most common intraocular malignancy in children, with a reported incidence ranging from 1 in 15,000 to 1 in 18,000 live births. Metastatic retinoblastoma is rare in developed countries, with a reported range from 4.8% in the United States to 5.8% in the United Kingdom. However, the frequency reported from developing countries varies from 9 to 11% at presentation. The mortality is very high owing to late presentations, delayed diagnosis compounded by socio-economic factors. The management of metastatic retinoblastoma is evolving, but it is still a challenge in pediatric oncology. We present a case of an extensive skeletal metastasis that initially presented as a massive orbital retinoblastoma.

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