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Year : 2014  |  Volume : 62  |  Issue : 11  |  Page : 1060-1063

Choroidal thickness profi le in healthy Indian subjects

1 Smt. Kanuri Santhamma Retina Vitreous Centre, Hyderabad, India
2 L.V. Prasad Eye Institute, Kode Venkatadri Chowdary Campus, Tadigadapa, Vijayawada, Andhra Pradesh, India
3 Center for Clinical Epidemiology and Biostatistics, L.V. Prasad Eye Institute, Kallam Anji Reddy Campus, Hyderabad, India

Correspondence Address:
Rajeev Reddy Pappuru
Smt. Kanuri Santhamma Retina Vitreous Centre, L.V. Prasad Eye Institute, Kallam Anji Reddy Campus, L.V. Prasad Marg, Banjara Hills, Hyderabad - 500 034, Andhra Pradesh
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0301-4738.146711

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Purpose: The aim was to study choroidal thickness (CT) and its profile based on location in healthy Indian subjects using Cirrus high definition (HD) optical coherence tomography. Materials and Methods: A total of 211 eyes of 115 healthy subjects with no retinal or choroidal disease were consecutively scanned using Cirrus HD 1 line raster scan mode without pupillary dilation. Eyes with any ocular disease or axial length (AXL) >24 mm or <20 mm were excluded. Experienced technician measured CT from the lower border of the retinal pigment epithelium (RPE) to the lower border of choroid. CT was measured from the posterior edge of the RPE to the choroid/sclera junction at 500-μm intervals up to 3000 μm temporal and nasal to the fovea. Generalized estimating equations were used to evaluate the correlation between CT at various locations and age, AXL, spherical equivalent, and macular thickness. Results: Mean age was 42.8 ± 13.6 years. Mean AXL was 22.84 ± 0.78 mm. Median spherical equivalent was 0.16 ± 0.64 D. Mean central macular thickness was 216.4 ± 30.03 μm. Choroidal was thinnest nasally and thickest subfoveally. On multivariate regression, age was the most significant factor affecting subfoveal CT (P = 0.000). Regression analysis showed an approximate decrease in CT of 1.18 μm every year. Conclusions: Our study provides CT profile in Indian healthy subjects in various age groups. CT depends on its location, subfoveal being the thickest and nasal being the thinnest. Age is a critical factor, which is negatively correlated with CT.

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