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Year : 2014  |  Volume : 62  |  Issue : 1  |  Page : 88-92

Changing paradigms of anti-VEGF in the Indian scenario

Vitre o-retinal and Ocular Oncology Services, Sankara Eye Hospitals, Bangalore, India

Correspondence Address:
P Mahesh Shanmugam
Vitreo-retinal and Ocular Oncology Services, Sankara Eye Hospitals, Bangalore
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0301-4738.126189

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Anti-vascular endothelial growth factors (VEGF) agents have revolutionized the treatment of retinal diseases. Use of anti-VEGF agents in the Indian Scenario present some unique challenges considering the absence of compounding pharmacies, poor penetrance of health insurance and limited affordability of the citizens of a developing economy. To study the changing paradigms of anti-VEGF use in the Indian scenario, all articles published by Indian authors, data from web-based surveys amongst Indian vitreo-retinal specialists were reviewed. In the paucity of compounding pharmacies in India, fractionation and injection techniques differ from those of developed countries. Frequent anti-VEGF monotherapy offers the best anatomical and visual results, but economics of scale do not allow the same in the Indian scenario, resulting in PRN dosing and combination of anti-VEGF with laser photocoagulation, being the commonly employed treatment protocols.

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