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REVIEW ARTICLE
Year : 2014  |  Volume : 62  |  Issue : 2  |  Page : 103-110

Etiopathogenesis of cataract: An appraisal


1 Research Associate, Ayurgenomics-TRISUTRA Project, Gujarat Ayurved University, Jamnagar, India
2 Department of Panchakarma, IPGT & RA, Gujarat Ayurved University, Jamnagar, India
3 Director, SDM Center for Research in Ayurveda and Allied Sciences, Udupi, Karnataka, India

Correspondence Address:
Varun B Gupta
Ph D (Sch), Pharmacology, C/o Dr. Manjusha R, Department of Shalakya, IPGT and RA, Gujarat Ayurved University, Jamnagar, Gujarat - 361 008
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0301-4738.121141

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Natural eye lens is a crystalline substance to produce a clear passage for light. Cataract is opacity within the clear lens of the eye and is the dominant cause of socio-medical problem i.e., blindness worldwide. The only available treatment of cataract is surgery. However, insufficient surgical facilities in poor and developing countries and post-operative complications inspire researchers to find out other modes of treatment for cataract. In this review, an attempt has been made to appraise various etiological factors of cataract to make their perception clear to build up counterpart treatment. Present study is an assortment of various available literatures and electronic information in view of cataract etiopathogenesis. Various risk factors have been identified in development of cataracts. They can be classified in to genetic factors, ageing (systemic diseases, nutritional and trace metals deficiencies, smoking, oxidative stress etc.), traumatic, complicated (inflammatory and degenerative diseases of eye), metabolic (diabetes, galactosemia etc.), toxic substances including drugs abuses, alcohol etc., radiation (ultraviolet, electromagnetic waves etc.) are implicated as significant risk factors in the development of cataract.


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