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Year : 2014  |  Volume : 62  |  Issue : 2  |  Page : 224-228

Outcomes of trabeculectomy in juvenile open angle glaucoma

1 VST Glaucoma Center, L. V. Prasad Eye Institute, Hyderabad, India
2 VST Glaucoma Center; Center for Clinical Epidemiology and Biostatistics, L. V. Prasad Eye Institute, Hyderabad, India

Correspondence Address:
Sirisha Senthil
L. V. Prasad Eye Institute, Kallam Anji Reddy campus, L. V. Prasad Marg, Road No. 2, Banjara Hills, Hyderabad 500034
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0301-4738.101074

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Purpose: This study was aimed at reporting the outcomes of trabeculectomy in primary juvenile open angle glaucoma (JOAG). Design: This study was a retrospective noncomparative case series. Materials and Methods: We included 60 eyes of 41 JOAG patients who underwent primary trabeculectomy without mitomycin-C (MMC) between 1995 and 2007. The primary outcome was success, defined as complete, if intraocular pressure (IOP) was >5 and ≤21 mmHg without medications or qualified if IOP was >5 and ≤21 mmHg with or without antiglaucoma medications. Secondary outcome measures were mean and percentage IOP reduction, complications, and risk factors for the failure of trabeculectomy. Results: The mean (±standard deviation) age at presentation was 24.1 ± 6.8 years (range, 12-35). Mean follow-up was 67 ± 41 months (range, 12-156). At 1 year, the probability of complete success was 92% (n = 56, 95% CI: 81-96%), at 3 years it was 89% (n = 47, 95% CI: 78-95%), and at the end of 5 years, it was 80% (n = 34, 95% CI: 65-89%). The probability of qualified success was 100% (n = 60) at 1 year, 98% (n = 51, 95% CI: 87-100%) at 3 years, and 96% (n = 36, 95% CI: 84-99%) at the end of 5 years. The mean IOP reduced from 35 ± 10 to 13 ± 2.5 mmHg (P < 0.001) after trabeculectomy. There was no serious postoperative complication. Young age was the only significant risk factor associated with the failure (odds ratio = 0.89, P = 0.03). Conclusion: Primary trabeculectomy without MMC has good success rates in JOAG.

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