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REVIEW ARTICLE
Year : 2014  |  Volume : 62  |  Issue : 7  |  Page : 768-772

Nanostructure-based platforms-current prospective in ophthalmic drug delivery


Department of Pharmaceutics, College of Pharmacy, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Kingdom of Saudi Arabia

Correspondence Address:
Rakesh Kumar Sharma
Department of Pharmaceutics, College of Pharmacy, King Saud Bin Abdulaziz University for Health Sciences, Riyadh
Kingdom of Saudi Arabia
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Source of Support: This editorial presents the recent work on ophthalmic drug delivery with emphasis given on the field of Nanotechnology. No funds have been received in order to carry out or culminate this work., Conflict of Interest: None


DOI: 10.4103/0301-4738.138301

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The topically applied drugs as drops are washed off from the eye in very short period, resulting in low ocular bioavailability of drugs. Number of approaches have been attempted to increase the bioavailability and the duration of action of ocular drugs. This review provides an insight into various novel approaches; hydrophilic nanogels, solid lipid nanoparticles, and nanosponges applied very recently in the delivery of insoluble drugs, prolonging the ocular residence time, minimize pre-corneal drug loss and, therefore, bioavailability and therapeutic efficacy of the drugs. Despite various scientific approaches, efficient ocular drug delivery remains a challenge for pharmaceutical scientists.


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