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Year : 2016  |  Volume : 64  |  Issue : 6  |  Page : 466-468

Solid variant of orbital angioleiomyoma: An unusual tumor at an unusual site

1 Ophthalmic Plastic Surgery and Ocular Oncology Services, Advanced Eye Hospital and Institute, Navi Mumbai, Maharashtra, India
2 Clinico Path Labs, Mumbai, Maharashtra, India
3 Metropolis Healthcare, Mumbai, Maharashtra, India

Correspondence Address:
Akshay Gopinathan Nair
Advanced Eye Hospital and Institute, 30, The Affaires, Palm Beach Road, Sanpada, Sector 17, Navi Mumbai - 400 705, Maharashtra
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0301-4738.187680

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We describe the clinicopathological features of a solid variant of orbital angioleiomyoma. A review of clinical records, diagnostic, and radiographic studies combined with histopathological evaluation with standard histochemical staining and immunohistochemistry was conducted. A 22-year-old male patient presented with a mass in the region of the left lacrimal gland that was gradually increasing over the past 2 years. Radiological and clinical examinations showed no signs suspicious of a malignancy and fine needle aspiration cytology was inconclusive. Therefore, an excision biopsy was performed. On histopathological examination, the picture was consistent with a benign spindle cell tumor. Immunohistochemistry showed positivity for CD 34 and CD 31 (markers for vascular endothelium). The tumor also showed positivity for smooth muscle actin and Ki-67 proliferative index was low. Angioleiomyomas are rarely encountered in the orbit and has features seen in leiomyoma as well as some vascular tumor elements. In most cases, surgical excision is usually curative.

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