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   Table of Contents      
LETTER TO THE EDITOR
Year : 2016  |  Volume : 64  |  Issue : 6  |  Page : 474-475

Response to: Choroidal thickness changes after dynamic exercise as measured by spectral-domain optical coherence tomography


1 Department of Ophthalmology, Kanuni Sultan Suleyman Education and Research Hospital, Istanbul, Turkey
2 Department of Ophthalmology, Gaziantep University, Gaziantep, Turkey
3 Department of Ophthalmology, Pamukkale University, Denizli, Turkey
4 Department of Ophthalmology, Ataturk Training and Research Hospital, Ankara, Turkey

Date of Web Publication3-Aug-2016

Correspondence Address:
Nihat Sayin
Atakent Mahallesi, 4. Cadde, C 2-7 Blok, Kat: 3 Daire: 13, Kücükcekmece, Istanbul
Turkey
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0301-4738.187687

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How to cite this article:
Sayin N, Kara N, Pekel G, Altinkaynak H. Response to: Choroidal thickness changes after dynamic exercise as measured by spectral-domain optical coherence tomography. Indian J Ophthalmol 2016;64:474-5

How to cite this URL:
Sayin N, Kara N, Pekel G, Altinkaynak H. Response to: Choroidal thickness changes after dynamic exercise as measured by spectral-domain optical coherence tomography. Indian J Ophthalmol [serial online] 2016 [cited 2020 Jun 1];64:474-5. Available from: http://www.ijo.in/text.asp?2016/64/6/474/187687

Sir,

We appreciate the interest in and comments. [1] Some controversy accompanies the presence of autoregulative mechanisms in choroidal circulation. There are a lot of vasoactive substances both endogenous and exogenous that have been shown to affect the choroidal thickness (CT). We want to emphasize autonomic innervation, and autoregulation of choroid in particular, and we agree that the autoregulatory mechanisms of choroidal blood flow are extremely complex. However, the choroidal blood flow is thought to exhibit only a small amount of autoregulation compared to the retinal blood flow. Therefore, the CT is shown to be influenced by numerous extrinsic factors including blood glucose and blood concentrations of oxygen and CO 2 . [2],[3] Thus, it is not surprising that hypothalamus is one of the main centers responsible for CT. On the other hand, the change in CT is thought to be obtained by redistribution of fluids or changes in the tonus of nonvascular smooth muscle. [4] Previous studies showed that choroidal blood flow changes in the contralateral eye when the ipsilateral eye was illuminated. [5] These results indicate that the response of choroidal blood flow is under neural control. Choroidal blood flow was found to decrease from light to dark adaptation whereas a decrease in retinal blood flow during illumination has been found in these studies. The author also mentions that lighting and light intensity of the room are important factors during optical coherence tomography (OCT) measurements, and it is very likely that they affect the test results. However, it may be necessary to ask how much light affect the CT measurements. However, we cannot answer this question, because when we searched the literature, we did not find any studies that evaluated the CT during light and dark by means of OCT. Hence, in our study, all measurements were performed under the standard room lighting.

Financial support and sponsorship

Nil.

Conflicts of interest

There are no conflicts of interest.

 
  References Top

1.
Sayin N, Kara N, Pekel G, Altinkaynak H. Choroidal thickness changes after dynamic exercise as measured by spectral-domain optical coherence tomography. Indian J Ophthalmol 2015;63:445-50.  Back to cited text no. 1
[PUBMED]  Medknow Journal  
2.
Xu J, Xu L, Du KF, Shao L, Chen CX, Zhou JQ, et al. Subfoveal choroidal thickness in diabetes and diabetic retinopathy. Ophthalmology 2013;120:2023-8.  Back to cited text no. 2
[PUBMED]    
3.
Altinkaynak H, Kara N, Sayin N, Günes H, Avsar S, Yazici AT. Subfoveal choroidal thickness in patients with chronic heart failure analyzed by spectral-domain optical coherence tomography. Curr Eye Res 2014;39:1123-8.  Back to cited text no. 3
    
4.
Ulas F, Dogan Ü, Keles A, Ertilav M, Tekçe H, Celebi S. Evaluation of choroidal and retinal thickness measurements using optical coherence tomography in non-diabetic haemodialysis patients. Int Ophthalmol 2013;33:533-9.  Back to cited text no. 4
    
5.
Fitzgerald ME, Gamlin PD, Zagvazdin Y, Reiner A. Central neural circuits for the light-mediated reflexive control of choroidal blood flow in the pigeon eye: A laser Doppler study. Vis Neurosci 1996;13:655-69.  Back to cited text no. 5
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