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BRIEF COMMUNICATION
Year : 2017  |  Volume : 65  |  Issue : 6  |  Page : 529-531

Management of a case of Candida albicans endogenous endophthalmitis with intravitreal caspofungin


1 Department of Ophthalmology, Kerala Institute of Medical Science, P.B.No.1, Anayara P.O, Trivandrum, Kerala, India
2 Department of Cancer Care, Kerala Institute of Medical Science, P.B.No.1, Anayara P.O, Trivandrum, Kerala, India
3 Neoretina Eye Care Institute, Dr.P.Ramchander House, 5-9-83/B, Nampally, Hyderabad, Telangana, India

Correspondence Address:
Harshali Manish Yadav
Department of Ophthalmology, Kerala Institute of Medical Sciences, P. No. 1, Anayara P., Thiruvananthapuram - 695 029, Kerala
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ijo.IJO_781_16

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We report a case of Candida albicans endogenous endophthalmitis treated with intravitreal caspofungin. The patient was a known case of acute lymphoblastic leukemia on chemotherapy and presented to us with features suggestive of endogenous endophthalmitis. He was treated initially with intravenous (IV) caspofungin and intravitreal amphotericin B. Patients condition worsened after IV caspofungin was replaced by amphotericin B necessitating a core vitrectomy. The patient was given the option of off-label caspofungin intravitreal injection for which the patient consented. There was a gradual improvement in the clinical picture. The situation worsened after the injections were stopped necessitating a revitrectomy. The study demonstrates the clinical efficacy of intravitreal caspofungin for the first time in human eyes.


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