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BRIEF COMMUNICATION
Year : 2017  |  Volume : 65  |  Issue : 8  |  Page : 741-743

Sympathetic ophthalmia related to conjunctival invasive squamous-cell carcinoma


1 Department of Ophthalmology, Hospital de Santa Maria; Visual Sciences Study Center, CECV, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal
2 Department of Ophthalmology, Vila de Franca de Xira Hospital, Lisbon, Portugal

Correspondence Address:
InÍs Leal
Department of Ophthalmology, Hospital de Santa Maria, Av. Prof. Egas Moniz, 1649-035 Lisbon
Portugal
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ijo.IJO_983_16

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Sympathetic ophthalmia (SO) is a rare, diffuse, bilateral, and granulomatous nonnecrotizing panuveitis that may follow intraocular penetrating trauma. Our aim is to report a rare case of SO following orbital exenteration. Orbital exenteration was performed on a 48-year-old african female due to conjunctival keratinizing squamous cell carcinoma with intraocular involvement of the left eye. Five days after the uneventful procedure, the patient presented signs and symptoms compatible with SO. Key differential diagnoses were excluded, and prompt and aggressive immunosuppression was started with a favourable but slow clinical response. This case highlights the fact that SO can also be induced by a neoplasm with intraocular invasion or by aggressive nonpenetrating surgery. While the underlying pathogenesis of SO is still not fully elucidated, we hereby contribute with a novel potential mechanism leading to its development.


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