|Year : 2018 | Volume
| Issue : 2 | Page : 300
“Comet-tail” lesions of pseudoxanthoma elasticum
Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India
|Date of Web Publication||30-Jan-2018|
Dr. Vinod Kumar
Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi
Source of Support: None, Conflict of Interest: None
|How to cite this article:|
Kumar V. “Comet-tail” lesions of pseudoxanthoma elasticum. Indian J Ophthalmol 2018;66:300
Comet-tail lesions are small, round, white bodies seen commonly in the inferior midperiphery of the retina [Figure 1]a. These are frequently associated with a tail, which always points toward the optic disc. On red-free imaging, comet-tail lesion appears as a bright dot with a less bright tail [Figure 1]b. Optical coherence tomography reveals them as hyporeflective spaces covered by hyperreflective margin, which overlie retinal pigment epithelium [Figure 1]c. Comet-tail lesions are considered to be pathognomonic of pseudoxanthoma elasticum (PE) and may appear earlier than other changes of PE such as angioid streaks and Peau d'orange.,
|Figure 1: Color (a), red-free (b) and optical coherence tomography imaging (c) of comet-tail lesions|
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| References|| |
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An update on the ocular phenotype in patients with Pseudoxanthoma elasticum. Front Genet 2013;4:14.