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LETTER TO THE EDITOR
Year : 2018  |  Volume : 66  |  Issue : 2  |  Page : 350

Comment on: Orbital dermatofibrosarcoma protuberans with frontal and ethmoid sinus involvement: A case report and brief review of literature


Department of Paediatrics, Al-Kindy College of Medicine, University of Baghdad, Baghdad, Iraq

Date of Web Publication30-Jan-2018

Correspondence Address:
Prof. Mahmood Dhahir Al-Mendalawi
Department of Paediatrics, Al-Kindy College of Medicine, University of Baghdad, P.O. Box 55302, Baghdad Post Office, Baghdad
Iraq
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ijo.IJO_945_17

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How to cite this article:
Al-Mendalawi MD. Comment on: Orbital dermatofibrosarcoma protuberans with frontal and ethmoid sinus involvement: A case report and brief review of literature. Indian J Ophthalmol 2018;66:350

How to cite this URL:
Al-Mendalawi MD. Comment on: Orbital dermatofibrosarcoma protuberans with frontal and ethmoid sinus involvement: A case report and brief review of literature. Indian J Ophthalmol [serial online] 2018 [cited 2019 Dec 7];66:350. Available from: http://www.ijo.in/text.asp?2018/66/2/350/224120



Sir,

I read with interest the case report by Sharma et al. on the orbital dermatofibrosarcoma protuberans (DFSP) with frontal and ethmoid sinus involvement in an Indian patient.[1] The authors nicely addressed the clinical picture, diagnostic workup, and the administered modalities of treatment. It is obvious that due to low immunity, patients infected with human immunodeficiency virus (HIV) are more vulnerable to various types of tumors in comparison to the immunocompetent individuals. Among these tumors, DFSP has been reported in HIV-positive patients.[2] To the best of my knowledge, HIV infection is an important health hazard in India. Although no recent data are yet present on the exact HIV seroprevalence in India, the available data pointed out to 0.26% seroprevalence compared with a global average of 0.2%.[3] I presume that HIV infection should be critically considered in the studied patient with the aggressive DFSP and protracted clinical course. Hence, the diagnostic algorithm of blood CD4 count and viral overload estimations for HIV infection was solicited. If that diagnostic algorithm was done and it revealed underling HIV infection, the case in question could be truly considered a novel case report as HIV-associated orbital DFSP has never been reported in the literature so far.

Financial support and sponsorship

Nil.

Conflicts of interest

There are no conflicts of interest.



 
  References Top

1.
Sharma D, Singh G, Kakkar N, Jha V. Orbital dermatofibrosarcoma protuberans with frontal and ethmoid sinus involvement: A case report and brief review of literature. Indian J Ophthalmol 2017;65:892-4.  Back to cited text no. 1
[PUBMED]  [Full text]  
2.
Sapadin AN, Gelfand JM, Howe KL, Phelps RG, Grand D, Rudikoff D, et al. Dermatofibrosarcoma protuberans in two patients with acquired immunodeficiency syndrome. Cutis 2000;65:85-8.  Back to cited text no. 2
    
3.
Paranjape RS, Challacombe SJ. HIV/AIDS in India: An overview of the Indian epidemic. Oral Dis 2016;22 Suppl 1:10-4.  Back to cited text no. 3
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