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Year : 2018  |  Volume : 66  |  Issue : 7  |  Page : 1006-1008

A case of human leukocyte antigen B-27-associated ocular hypotony successfully treated with golimumab

1 Department of Uvea and Intraocular Inflammation, Sankara Nethralaya, Chennai, Tamil Nadu, India
2 Department of Glaucoma, Sankara Nethralaya, Chennai, Tamil Nadu, India
3 Departement of Uvea, Sankara Nethralaya, Kolkata, India
4 Department of Rheumatology, Apollo Hospital, Chennai, Tamil Nadu, India

Correspondence Address:
Parthopratim Dutta Majumder
Department of Uvea, Sankara Nethralaya, 18, College Road, Nungambakkam, Chennai - 600 006, Tamil Nadu
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ijo.IJO_120_18

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A 42-year-old male presented to us after an episode of acute anterior human leukocyte antigen (HLA)-B27-associated uveitis, and intraocular pressure (IOP) in the right eye was 4 mmHg. Ultrasound biomicroscopy revealed ciliary body edema with supraciliary effusion. He was on a frequent topical corticosteroid, and oral steroid in addition to receiving a periocular injection depot corticosteroid 20 days back. He was started on treatment with subcutaneous golimumab (GLM). After a month, his IOP in the right eye was 14 mm of Hg with UBM showing resolution of ciliary body edema. GLM can be useful in the management of steroid-resistant cases of HLA B-27-associated ocular hypotony.

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