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CASE REPORT
Year : 2018  |  Volume : 66  |  Issue : 7  |  Page : 1012-1014

Management of Candida glabrata infectious crystalline keratopathy with endophthalmitis following penetrating keratoplasty


1 Cornea and Anterior Segment Services, Tej Kohli Cornea Institute, LV Prasad Eye Institute, Hyderabad, Telangana, India
2 Jhaveri Microbiology Centre, LV Prasad Eye Institute, Hyderabad, Telangana, India
3 Smt. Kanuri Santhamma Centre for Vitreo Retinal Diseases, LV Prasad Eye Institute, Hyderabad, Telangana, India
4 Department of Ophthalmology, Ministry of Health, Al Nahdha Hospital, Muscat, Oman

Correspondence Address:
Sunita Chaurasia
Tej Kohli Cornea Institute, LV Prasad Eye Institute, Kallam Anji Reddy Campus, Banjara Hills, Hyderabad - 500 034, Telangana
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ijo.IJO_1106_17

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A 33-year-old male underwent an optical keratoplasty elsewhere in the right eye following which he developed endophthalmitis and subsequently underwent a pars plana vitrectomy and lensectomy. At presentation, he had a deep stromal crystalline infiltration along the graft–host junction. A large therapeutic keratoplasty was performed, and the excised corneal button was evaluated. Histopathology revealed gram-positive round-to-oval budding structures and microbiology identified the organism as Candida glabrata. He was treated with antifungals in the postoperative period. At 4 months after therapeutic keratoplasty, the patient developed recurrent endophthalmitis, following stoppage of antifungals. The treatment was reinstituted for another year, and the patient did well with a clear graft at 18-month-follow-up period after the recurrence episode. Management of infectious crystalline keratopathy with endophthalmitis is a challenging situation and requires long-term treatment.


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