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CASE REPORT
Year : 2018  |  Volume : 66  |  Issue : 7  |  Page : 1042-1044

Endocrine mucin-producing sweat gland carcinoma of the eyelid: A clinical and histological conundrum


1 Department of Ophthalmic Plastic Surgery & Ocular Oncology Services, Orbit Eye Hospital; Department of Ophthalmic Plastic Surgery & Ocular Oncology Services, Advanced Eye Hospital and Institute, Mumbai, Maharashtra, India
2 Department of Pathology, Suburban Diagnostics Pvt. Ltd, Mumbai, Maharashtra, India
3 Department of Ophthalmic Plastic Surgery & Ocular Oncology Services, Orbit Eye Hospital, Mumbai, Maharashtra, India

Correspondence Address:
Akshay Gopinathan Nair
Orbit Eye Hospital, Jogeshwari, Mumbai, Maharashtra
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ijo.IJO_36_18

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A 60-year-old male presented with a 6-month-old history of a left upper lid mass. The mass was excised, and histopathological evaluation showed a well-circumscribed, multinodular, intradermal tumor consisting of round-to-oval cells with round nuclei and mucin filled cysts. On immunohistochemical analysis, the tumor cells stained positively for cytokeratin (CK)-7, CK-8, estrogen receptor (ER), progesterone receptor (PR), mucicarmine, synaptophysin, gross cystic disease fluid protein-15 (GCDFP-15), and neuron-specific enolase (NSE). A diagnosis of endocrine mucin-producing sweat gland carcinoma (EMPSGC) of the eyelid was made and at 6-month follow-up, no recurrence was noted. In this communication, we discuss the pathology and treatment options of EMPSGC of the eyelid. Although an uncommon entity, EMPSGC may be considered as a differential when encountered with a suspicious, potentially malignant eyelid mass.


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