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CASE REPORT
Year : 2018  |  Volume : 66  |  Issue : 9  |  Page : 1342-1344

Topiramate-induced acute angle closure with severe panuveitis: A challenging case report


1 Uveitis and Ocular Immunology Services, Narayana Nethralaya, Bangalore, Karnataka, India
2 Glaucoma Services, Narayana Nethralaya, Bangalore, Karnataka, India
3 Cataract and Refractive Surgeries, Narayana Nethralaya, Bangalore, Karnataka, India

Correspondence Address:
Dr. Padmamalini Mahendradas
Uveitis and Ocular Immunology Services, Narayana Nethralaya, 121/C, Chord Road, 1st ‘R’ Block, Rajajinagar, Bengaluru - 560 010, Karnataka
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ijo.IJO_1192_17

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A 36-year-old female presented with the complaints of pain, photophobia, redness, and sudden diminution of vision in both the eyes following topiramate for migraine treatment. On examination, there was panuveitis with angle-closure glaucoma in both the eyes with fibrinous exudate with pigments in the anterior chamber of the left eye. B scan revealed increased choroidal thickness in both the eyes. Serial anterior segment optical coherence tomography scans were done in the left eye to demonstrate the gradual resolution of the fibrin material from the anterior chamber. There was complete resolution of inflammation in both eyes following discontinuation of topiramate and treatment with systemic and topical steroids. There was an improvement in visual acuity in the left eye following complicated cataract surgery.


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