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OPHTHALMIC IMAGE
Year : 2019  |  Volume : 67  |  Issue : 10  |  Page : 1724

Resolution of Kayser–Fleischer ring in Wilson disease


Advanced Eye Centre, Post Graduate Institute of Medical Education and Research, Chandigarh, India

Date of Web Publication23-Sep-2019

Correspondence Address:
Dr. Jagat Ram
Advanced Eye Centre, Post Graduate Institute of Medical Education and Research, Sector 12, Chandigarh - 160 012
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ijo.IJO_957_19

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How to cite this article:
Khurana S, Gupta PC, Ram J. Resolution of Kayser–Fleischer ring in Wilson disease. Indian J Ophthalmol 2019;67:1724

How to cite this URL:
Khurana S, Gupta PC, Ram J. Resolution of Kayser–Fleischer ring in Wilson disease. Indian J Ophthalmol [serial online] 2019 [cited 2019 Oct 18];67:1724. Available from: http://www.ijo.in/text.asp?2019/67/10/1724/267472



A 6-year-old child with Wilson disease and autoimmune hepatitis presented to cornea clinic for routine ocular examination with unaided vision of 20/20 OU. Microscopic slit lamp examination revealed bilateral thick, circumferential green copper deposition on Descemet's membrane of the cornea suggestive of Kayser–Fleischer (KF) ring [Figure 1]a. After being treated with penicillamine, oral steroids, and immunosuppression for 1 year, KF ring had decreased significantly [Figure 1]b. KF ring is most commonly seen in Wilson disease [1] but can also be seen in chronic active hepatitis, primary biliary cirrhosis, hepatocellular disorders, and intraocular foreign body containing copper.[2]
Figure 1: (a) Kayser–Fleischer ring, seen as circumferential green pigment deposition at the level of Descemet's membrane, before treatment. (b) Decrease in KF ring after treatment

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Declaration of patient consent

The authors certify that they have obtained all appropriate patient consent forms. In the form the patient(s) has/have given his/her/their consent for his/her/their images and other clinical information to be reported in the journal. The patients understand that their names and initials will not be published and due efforts will be made to conceal their identity, but anonymity cannot be guaranteed.

Financial support and sponsorship

Nil.

Conflicts of interest

There are no conflicts of interest.



 
  References Top

1.
Sullivan CA, Chopdar A, Shun-Shin GA. Dense Kayser-Fleischer ring in asymptomatic Wilson's disease (hepatolenticular degeneration). Br J Ophthalmol 2002;86:114.  Back to cited text no. 1
    
2.
Frommer D, Morris J, Sherlock S, Abrams J, Newman S. Kayser-Fleischer like rings in patients without Wilson's disease. Gastroenterology 1977;72:1331-5.  Back to cited text no. 2
    


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