|Year : 2019 | Volume
| Issue : 10 | Page : 1725
Anterior segment optical coherence tomography to differentiate adenoviral subepithelial infiltrates and scars
Nikhil S Gokhale
Gokhale Eye Hospital, Mumbai, Maharashtra, India
|Date of Web Publication||23-Sep-2019|
Dr. Nikhil S Gokhale
Gokhale Eye Hospital, Anant Building, Gokhale Road South, Dadar West, Mumbai - 400 028, Maharashtra
Source of Support: None, Conflict of Interest: None
|How to cite this article:|
Gokhale NS. Anterior segment optical coherence tomography to differentiate adenoviral subepithelial infiltrates and scars. Indian J Ophthalmol 2019;67:1725
|How to cite this URL:|
Gokhale NS. Anterior segment optical coherence tomography to differentiate adenoviral subepithelial infiltrates and scars. Indian J Ophthalmol [serial online] 2019 [cited 2020 Jan 20];67:1725. Available from: http://www.ijo.in/text.asp?2019/67/10/1725/267470
Subepithelial corneal infiltrates often follow adenoviral keratoconjunctivitis. They usually resolve over time, but in some, these can progress to permanent corneal scars. Anterior segment- optical coherence tomography (S-OCT) can be a very useful tool to differentiate reversible infiltrates from irreversible scars and obviates the need for a steroid trial.
Subepithelial corneal infiltrates [Figure 1]a appear on AS-OCT patchy, anterior stromal hyperreflective lesions with an intact Bowman's membrane and a uniform epithelial thickness [Figure 1]b. On the other hand, scars [Figure 1]c on AS-OCT appear as hyperreflective plaque-like lesions in the anterior stroma with disruption of the Bowman's membrane and variable epithelial thickness due to epithelial remodeling [Figure 1]d.
|Figure 1: (a) Subepithelial corneal infiltrates. (b) Patchy hyperreflective lesions involving the anterior stroma just beneath the intact Bowman's membrane. (c) Permanent adenoviral scars. (d) Hyperreflective plaque-like lesions in the anterior stroma with disruption of the Bowman's membrane and variable epithelial thickness|
Click here to view
Financial support and sponsorship
Conflicts of interest
There are no conflicts of interest.
| References|| |
Dawson CR, Hanna L, Wood TR, Despain R. Adenovirus type 8 keratoconjunctivitis in the United States. 3. Epidemiologic, clinical, and microbiologic features. Am J Ophthalmol 1970;69:473-80.