Glyxambi
Home About us Editorial board Ahead of print Current issue Search Archives Submit article Instructions Subscribe Contacts Login 
  • Users Online: 2822
  • Home
  • Print this page
  • Email this page


 
   Table of Contents      
OPHTHALMIC IMAGE
Year : 2019  |  Volume : 67  |  Issue : 10  |  Page : 1731

Unilateral giant macular hole in a case of Alport syndrome


Department of Vitreoretina and Uveitis Services, L V Prasad Eye Institute, GMRV Campus, Visakhapatnam, Andhra Pradesh, India

Date of Web Publication23-Sep-2019

Correspondence Address:
Dr. Avinash Pathengay
Department of Vitreoretina and Uveitis Services, L V Prasad Eye Institute, GMRV Campus, Visakhapatnam - 530 040, Andhra Pradesh
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ijo.IJO_650_19

Rights and Permissions

How to cite this article:
Panchal B, Doshi S, Pathengay A. Unilateral giant macular hole in a case of Alport syndrome. Indian J Ophthalmol 2019;67:1731

How to cite this URL:
Panchal B, Doshi S, Pathengay A. Unilateral giant macular hole in a case of Alport syndrome. Indian J Ophthalmol [serial online] 2019 [cited 2019 Oct 19];67:1731. Available from: http://www.ijo.in/text.asp?2019/67/10/1731/267456



A 27-year-old man presented to us with right eye blurred vision since childhood. He was a known case of Alport syndrome. The best corrected visual acuity was 20/400 in the right eye and 20/20 in the left eye. The anterior segment was unremarkable. The right eye fundus showed a single giant macular hole with vitreous opacities. The macular hole showed a thickened edge with hypopigmented retinal pigment epithelium underneath the hole suggestive of chronicity [Figure 1]. The left eye fundus was unremarkable. The macular hole measured 3519 × 3111 microns on the ocular coherence tomography. On reviewing the literature, only Ozdek et al.[1] have reported a larger macular hole than our case (3800 × 3200 microns). In addition to anterior lenticonus, development of large macular holes is an important cause for loss of central vision in patients with Alport syndrome. The exact etiology of such large macular holes is unclear, however, an abnormal Type IV collagen in the internal limiting membrane may contribute to macular hole formation.[2]
Figure 1: (a) Fundus photo showing the giant macular hole with vitreous opacity. The macular hole showed a thickened edge with hypopigmented retinal pigment epithelium underneath the hole suggestive of chronicity. (b) The vertical scan on OCT showed 3519 × 3111 microns sized macular hole with the presence of outer retinal cystic spaces

Click here to view


Declaration of patient consent

The authors certify that they have obtained all appropriate patient consent forms. In the form the patient(s) has/have given his/her/their consent for his/her/their images and other clinical information to be reported in the journal. The patients understand that their names and initials will not be published and due efforts will be made to conceal their identity, but anonymity cannot be guaranteed.

Financial support and sponsorship

Nil.

Conflicts of interest

There are no conflicts of interest.



 
  References Top

1.
Ozdek SC, Pehlivanli Z, Sari A, Hasanreisoglu B. Bilateral giant macular hole in a patient with chronic renal failure. Surg Lasers Imaging Retina 2003;34:480-2.  Back to cited text no. 1
    
2.
Shah SN, Weinberg DV. Giant macular hole in alportsyndrome. Ophthalmic Genet 2010;31:94-7.  Back to cited text no. 2
    


    Figures

  [Figure 1]



 

Top
 
 
  Search
 
    Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
    Access Statistics
    Email Alert *
    Add to My List *
* Registration required (free)  

 
  In this article
References
Article Figures

 Article Access Statistics
    Viewed146    
    Printed0    
    Emailed0    
    PDF Downloaded36    
    Comments [Add]    

Recommend this journal