CASE REPORT |
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Year : 2019 | Volume
: 67
| Issue : 12 | Page : 2066-2068 |
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Severe necrotising inflammatory skin reaction to topical 5-fluorouracil
Nikhil S Gokhale
Gokhale Eye Hospital, Anant Building, Gokhale Road South, Dadar West, Mumbai, Maharashtra, India
Correspondence Address:
Dr. Nikhil S Gokhale Gokhale Eye Hospital, Anant Building, Gokhale Road South, Dadar West, Mumbai, Maharashtra - 400 028 India
Source of Support: None, Conflict of Interest: None | Check |
DOI: 10.4103/ijo.IJO_373_19
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I report two patients who developed a severe necrotising inflammatory skin reaction with ulceration and hemorrhagic crusting during the first cycle of chemotherapy with 1% 5-Fluorouracil eye drops for Ocular surface squamous neoplasia. The skin reaction subsided on stoppage of the drops and the use of a steroid ointment. 5 fluorouracil therapy was terminated and the patients were shifted to interferon therapy subsequently.
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