ORIGINAL ARTICLE |
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Year : 2019 | Volume
: 67
| Issue : 1 | Page : 69-74 |
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Safety and efficacy of dexamethasone implant along with phacoemulsification and intraocular lens implantation in children with juvenile idiopathic arthritis associated uveitis
Jitender Jinagal1, Gaurav Gupta1, Aniruddha Agarwal1, Kanika Aggarwal1, Madhuri Akella1, Vishali Gupta1, Deepti Suri2, Anju Gupta2, Surjit Singh2, Jagat Ram1
1 Advanced Eye Centre, Post Graduate Institute of Medical Education and Research, Sector 12, Chandigarh, India 2 Department of Pediatrics, Division of Allergy and Immunology, Post Graduate Institute of Medical Education and Research, Sector 12, Chandigarh, India
Correspondence Address:
Dr. Jagat Ram Advanced Eye Center, Post Graduate Institute of Medical Education and Research (PGIMER), Sector 12, Chandigarh - 160 012 India
Source of Support: None, Conflict of Interest: None | Check |
DOI: 10.4103/ijo.IJO_713_18
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Purpose: To assess the safety and efficacy of intraoperative intravitreal dexamethasone implant in patients of juvenile idiopathic arthritis (JIA)-associated uveitis undergoing phacoemulsification with posterior chamber intraocular lens (PCIOL) implantation. Methods: Retrospectively, data of patients with JIA-associated uveitis undergoing phacoemulsification with PCIOL implantation with intraoperative dexamethasone implant injection were analyzed. Patients with a minimum follow-up of 6 months were included. Primary outcome measures were ocular inflammation, intraocular pressure (IOP), best-corrected visual acuity (BCVA), and worsening of uveitis. Results: 8 eyes of 6 patients were included. BCVA was significantly improved at 1, 3, and 6 months postoperatively 0.20 ± 0.09, P = 0.008; 0.18 ± 0.11, P = 0.008; and 0.24 ± 0.11, P = 0.01, respectively. No statistical difference noted in mean IOP at various follow-up visits. None developed worsening of uveitis or Cystoid macular edema. Conclusion: Intraoperative intravitreal dexamethasone implant is a safe and effective in preventing and managing the postoperative inflammation in children with JIA-associated uveitic cataract.
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