|Year : 2019 | Volume
| Issue : 4 | Page : 556
Management of retinal artery macroaneurysm exudation in Wyburn-Mason syndrome with intravitreal ranibizumab
Anmol U Naik, Muna Bhende, Ambika Selvakumar, Vikas Khetan
Shri Bhagwan Mahavir Vitreoretinal Services, Sankara Nethralaya, Medical Research Foundation, Chennai, Tamil Nadu, India
|Date of Web Publication||22-Mar-2019|
Dr. Vikas Khetan
Senior Consultant, Shri Bhagwan Mahavir Vitreoretinal Services, Sankara Nethralaya, Medical Research Foundation, 18 College Road, Chennai - 600 006, Tamil Nadu
Source of Support: None, Conflict of Interest: None
|How to cite this article:|
Naik AU, Bhende M, Selvakumar A, Khetan V. Management of retinal artery macroaneurysm exudation in Wyburn-Mason syndrome with intravitreal ranibizumab. Indian J Ophthalmol 2019;67:556
|How to cite this URL:|
Naik AU, Bhende M, Selvakumar A, Khetan V. Management of retinal artery macroaneurysm exudation in Wyburn-Mason syndrome with intravitreal ranibizumab. Indian J Ophthalmol [serial online] 2019 [cited 2019 Apr 23];67:556. Available from: http://www.ijo.in/text.asp?2019/67/4/556/254716
A 21-year-old female with a history of right-sided thalamostriate arteriovenous malformation (AVM) between the right anterior cerebral artery and right ophthalmic artery presented with decreased vision in the right eye. Best-corrected visual acuity (BCVA) was 6/18, N12 in the right eye and 6/6, N6 in the left eye. Fundus revealed a retinal racemose haemangioma (RRH) with a retinal artery macroaneurysm (RAM) [Figure 1]a. The left eye was within normal limits. A swept-source optical coherence tomography angiography (SSOCT-A) demonstrated marked retinal thickening and subretinal fluid (SRF) on B-scan [Figure 1]b with angiographic image demonstrating the high blood flow RAM lesion in superficial retina [[Figure 1]b, inset]. A diagnosis of Wyburn-Mason syndrome with a leaking RAM was made. Intravitreal ranibizumab (0.5 mg in 0.1 ml) injection was administered. At 1-month follow-up, the thickening and SRF had resolved [Figure 1]c and [Figure 1]d. The arteriolar and venular turgidity too had decreased. At the last follow-up, at a period of 4 months post-injection, there was no recurrence and BCVA in the right eye was maintained at 6/9, N6. To the best of our knowledge, this is the first report of RAM exudation in a known case of Wyburn-Mason syndrome which was successfully managed with intravitreal ranibizumab.
|Figure 1: Retinal artery macroaneurysm exudation with retinal racemose haemangioma in Wyburn-Mason syndrome. Clinical picture (a) with corresponding swept-source optical coherence tomography (SSOCT) B-scan and angiographic images (b) at presentation. At 1-month follow-up post-intravitreal ranibizumab, there was a significant reduction in retinal thickening and subretinal fluid, as seen clinically (c) and in OCT B-scan image (d)|
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