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Year : 2019  |  Volume : 67  |  Issue : 6  |  Page : 958-960

In-utero ultrasonography detection of fetal retinoblastoma and neonatal selective ophthalmic artery chemotherapy

1 Horus Specialty Eye Care, JP Nagar 2nd Phase, Bengaluru, Karnataka, India; Women's and Children's Medical Center, Guangzhou, China
2 Women's and Children's Medical Center, Guangzhou, China
3 Dongguan Women and Children Hospital, Dongguan, Guangdong, China

Correspondence Address:
Dr. Fairooz P Manjandavida
Horus Specialty Eye Care, JP Nagar 2nd Phase, Bangalore - 560 078, Karnataka

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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ijo.IJO_340_19

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We report a case of non-familial, sporadic fetal retinoblastoma (RB) that was accidently detected at 39 weeks of gestation on pre-natal ultrasonography in left eye (OS). Post-natal examination revealed Group A and, Group D RB in right eye (OD) and OS, respectively. At 35 days, selective ophthalmic artery intra-arterial chemotherapy (IAC) was performed in OS and laser for OD. Pre-natal ultrasound and its application in RB are limited to those cases with a strong genetic predisposition. Our case was accidently detected at late gestation with no familial or genetic predisposition. In addition, this was the youngest reported case that received IAC on literature review.

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