|Year : 2019 | Volume
| Issue : 7 | Page : 1186
Melanocytoma of the optic disc - Clinical spectrum
Simar Rajan Singh, Aditi Mehta, Mohit Dogra, Mangat Ram Dogra
Advanced Eye Centre, Postgraduate Institute of Medical Education and Research, Chandigarh, India
|Date of Web Publication||25-Jun-2019|
Dr. Mohit Dogra
Advanced Eye Center, Postgraduate Institute of Medical Education and Research, Chandigarh
Source of Support: None, Conflict of Interest: None
|How to cite this article:|
Singh SR, Mehta A, Dogra M, Dogra MR. Melanocytoma of the optic disc - Clinical spectrum. Indian J Ophthalmol 2019;67:1186
|How to cite this URL:|
Singh SR, Mehta A, Dogra M, Dogra MR. Melanocytoma of the optic disc - Clinical spectrum. Indian J Ophthalmol [serial online] 2019 [cited 2020 Feb 21];67:1186. Available from: http://www.ijo.in/text.asp?2019/67/7/1186/261047
Melanocytoma of the optic disc, first described by Zimmermann, is a benign hamartoma arising from melanocytes in the disc. [Figure 1]a shows a typical dark-brown pigmented melanocytoma overlying and obscuring the disc with involvement of the adjacent choroid and retina. Over time, melanocytoma can lead to local compressive sequalae-like branch retinal artery occlusion [Figure 1]b and ischemic optic neuropathy [Figure 1]c. Rare, malignant transformation can occur in 1-2% of the cases with progressive increase in size and extensive involvement of the disc [Figure 1]d.,, Cases with melanocytoma require yearly follow-up with photographic documentation to detect these changes early.
|Figure 1: Melanocytoma of the Optic Disc. (a) Typical dark-brown lesion overlying the disc with involvement of surrounding retina and choroid. (b) Melanocytoma with branch retinal artery occlusion. (c) Melanocytoma with compressive ischemic optic neuropathy. (d) Melanocytoma with extensive involvement of the disc and surrounding retina and progressive increase in size, suggestive of malignant transformation|
Click here to view
Financial support and sponsorship
Conflicts of interest
There are no conflicts of interest.
| References|| |
Shields JA, Demirci H, Mashayekhi A, Eagle RC, Shields CL. Melanocytoma of the optic disk: A review. Surv Ophthalmol 2006;51:93-104.
Rishi P, Venkatesh R. Central retinal artery occlusion secondary to optic disk melanocytoma. Retin Cases Brief Rep 2012;6:212-5.
Shields JA, Demirci H, Mashayekhi A, Shields CL. Melanocytoma of optic disc in 115 cases: The 2004 Samuel Johnson memorial lecture, part 1. Ophthalmology 2004;111:1739-46.
Erzurum SA, Jampol LM, Territo C, O'Grady R. Primary malignant melanoma of the optic nerve simulating a melanocytoma. Arch Ophthalmol. 1992;110:684-6.
Loeffler KU, Tecklenborg H. Melanocytoma-like growth of a juxtapapillary malignant melanoma. Retina 1992;12:29-34.