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LETTERS TO THE EDITOR
Year : 2020  |  Volume : 68  |  Issue : 7  |  Page : 1505-1506

Comments on: Using corneal graft from keratoconic donor for lamellar and penetrating keratoplasties


Department of Cornea and Refractive Surgery, Medical Research Foundation, Sankara Nethralaya, Chennai, Tamil Nadu, India

Date of Web Publication25-Jun-2020

Correspondence Address:
Dr. Manokamna Agarwal
Department of Cornea and Refractive Surgery, Sankara Nethralaya, No. 21, Pycrofts Garden Road, Chennai - 600 006, Tamil Nadu
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ijo.IJO_138_20

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How to cite this article:
Agarwal M, Natarajan R. Comments on: Using corneal graft from keratoconic donor for lamellar and penetrating keratoplasties. Indian J Ophthalmol 2020;68:1505-6

How to cite this URL:
Agarwal M, Natarajan R. Comments on: Using corneal graft from keratoconic donor for lamellar and penetrating keratoplasties. Indian J Ophthalmol [serial online] 2020 [cited 2020 Jul 10];68:1505-6. Available from: http://www.ijo.in/text.asp?2020/68/7/1505/287479



Dear Editor:

We read with interest the use of keratoconic donor corneas for elective endothelial keratoplasty and emergency penetrating keratoplasty.[1] Collagen cross-linking (CXL) treatment is the current gold standard for imparting biomechanical stability in keratoconus.[2] CXL has also been done to strengthen the donor cornea used as carrier graft for Boston keratoprosthesis to avoid sterile melts.[3] We and others have demonstrated fortification of the donor cornea with preoperative CXL to prevent recurrent infection in therapeutic penetrating keratoplasty done for infective keratitis.[4],[5]

We wish to point out that cross-linking may similarly be performed on a keratoconic donor cornea which has to be used for full-thickness transplant in exigent situations. This may help confer biomechanical stability when grafted in the host eye.

Financial support and sponsorship

Nil.

Conflicts of interest

There are no conflicts of interest.



 
  References Top

1.
Kymionis GD, Tabibian D, Voulgari N, Fabro F, Grentzelos MA. Using corneal graft from keratoconic donor for lamellar and penetrating keratoplasties. Indian J Ophthalmol 2020;68:226-9.  Back to cited text no. 1
[PUBMED]  [Full text]  
2.
Blackburn BJ, Jenkins MW, Rollins AM, Dupps WJ. A review of structural and biomechanical changes in the cornea in aging, disease, and photochemical crosslinking. Front Bioeng Biotechnol 2019;7:66.  Back to cited text no. 2
    
3.
Kanellopoulos AJ, Asimellis G. Long-term safety and efficacy of high-fluence collagen crosslinking of the vehicle cornea in Boston keratoprosthesis type 1. Cornea 2014;33:914-8.  Back to cited text no. 3
    
4.
Popat K, Natarajan R. Safety and efficacy of collagen cross linking for donor corneal button in therapeutic penetrating keratoplasty. Indian J Clin Exp Ophthalmol 2019;5:61-5.  Back to cited text no. 4
    
5.
Titiyal JS, Karunakaran A, Kaur M, Rathi A, Agarwal T, Sharma N. Collagen cross-linked therapeutic grafts in fungal keratitis. Ophthalmol 2018;125:1471-3.  Back to cited text no. 5
    




 

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