|Year : 2020 | Volume
| Issue : 8 | Page : 1666
Recurrent corneal erosion image by scanning electron microscopy
Jorge Peraza Nieves, Carlos Rocha de Lossada, Noelia Sabater Cruz, Josep Torras Sanvicens
Hospital Clinic of Barcelona, Sabino de Arana 1, Barcelona, Spain
|Date of Web Publication||24-Jul-2020|
Dr. Carlos Rocha de Lossada
Hospital Clinic of Barcelona, Sabino de Arana 1, Barcelona
Source of Support: None, Conflict of Interest: None
|How to cite this article:|
Peraza Nieves J, Rocha de Lossada C, Sabater Cruz N, Torras Sanvicens J. Recurrent corneal erosion image by scanning electron microscopy. Indian J Ophthalmol 2020;68:1666
|How to cite this URL:|
Peraza Nieves J, Rocha de Lossada C, Sabater Cruz N, Torras Sanvicens J. Recurrent corneal erosion image by scanning electron microscopy. Indian J Ophthalmol [serial online] 2020 [cited 2020 Aug 12];68:1666. Available from: http://www.ijo.in/text.asp?2020/68/8/1666/290434
Corneal epithelial basement membrane (EBM) is positioned between basal surface of the epithelial cells and on top of the Bowman layer (BL). It consists of 0.33 μm multilayered extracellular matrix of collagens, laminins, heparan sulfate proteoglycans, and nidogens.
Recurrent corneal erosions (RCE) are characterized by sudden onset of eye pain typically in eyes that have had suffered from a previous sharp trauma or patients suffering from some corneal dystrophy., The trauma induces a lack of attachment of cell-to-cell or cell-to-matrix causing a disruption.
We simulated a sharp trauma with a 30 G needle at the epithelium of a corneoscleral-rim from a donor cornea and analyzed it using scanning electron microscopy [Figure 1] to show how RCE appear and to better understand the anatomical disruption and attachment of the EBM to BL to search new therapeutic targets.
|Figure 1: Yellow arrows: epithelial basement membrane, red arrow: Bowmann layer, blue arrow: sub-basal nerve foramen|
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Conflicts of interest
There are no conflicts of interest.
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