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REVIEW ARTICLE
Year : 2020  |  Volume : 68  |  Issue : 9  |  Page : 1750-1763

Interleukins and cytokine biomarkers in uveitis


1 Uveitis Services, Aravind Eye Hospital, Pondicherry, India
2 Department of Ocular Pathology, Uveitis and Neuro-Ophthalmology, Sri Sankaradeva Nethralaya, Guwahati, Assam, India
3 Department of Ophthalmology, Koc University Medical School; Koc University Center for Translational Medicine Research, Istanbul; Department of Ophthalmology, Gazi University, School of Medicine, Ankara, Turkey
4 Assistant Professor of Clinical Ophthalmology, USC Roski Eye Institute, Los Angeles, USA
5 USC Roski Eye Institute, Los Angeles, USA
6 Uveitis Services, Aravind Eye Hospital, Coimbatore, Tamil Nadu, India
7 Uveitis Services, Aravind Eye Hospital, Chennai, Tamil Nadu, India
8 Aravind Eye Hospital, Pondicherry, India

Correspondence Address:
Dr. S Balamurugan
Uveitis Services, Aravind Eye Hospital, Pondicherry
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ijo.IJO_564_20

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Interleukins and cytokines are involved in the pathogenesis of uveitis of heterogeneous origin. Understanding the basics of the ocular immune privilege is a fulcrum to discern their specific role in diverse uveitis to potentially translate as therapeutic targets. This review attempts to cover these elements in uveitis of infectious, noninfectious and masquerade origin. Insights of the molecular targets in novel therapy along with the vision of future research are intriguing.


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