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Year : 2020  |  Volume : 68  |  Issue : 9  |  Page : 1808-1817

Ocular tuberculosis: Where are we today?

1 Moorfields Eye Hospital, NHS Foundation Trust, London, United Kingdom
2 Moorfields Eye Hospital, NHS Foundation Trust, London, United Kingdom; National Healthcare Group Eye Institute, Tan Tock Seng Hospital; Singapore Eye Research Institute, Singapore
3 Department of Ophthalmology, Lilavati Hospital and Research Center, Mumbai, India
4 LV Prasad Eye Institute, Bhubaneswar, India
5 Byres Eye Institute, Stanford University, Palo Alto, California, USA
6 Advanced Eye Centre, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India

Correspondence Address:
Prof. Vishali Gupta
Advanced Eye Centre, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh 160012
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ijo.IJO_1451_20

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Diagnosis and management of ocular tuberculosis (OTB) poses a significant challenge. Mixed ocular tissue involvement and lack of agreement on best practice diagnostic tests together with the global variations in therapeutic management contributed to the existing uncertainties regarding the outcome of the disease. The current review aims to update recent progress on OTB. In particular, the Collaborative Ocular Tuberculosis Study (COTS) group recently standardized a nomenclature system for defining clinical phenotypes, and also proposed consensus guidelines and an algorithmic approach for management of different clinical phenotypes of OTB. Recent developments in experimental research and innovations in molecular diagnostics and imaging technology have provided a new understanding in the pathogenesis and natural history of the disease.

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