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Year : 2020  |  Volume : 68  |  Issue : 9  |  Page : 1988-1990

Tofacitinib in recalcitrant scleritis: First case report from India

1 Department of Uvea, Sankara Nethralaya, Chennai, Tamil Nadu, India
2 Department of Rheumatology, Apollo Hospital, Chennai, Tamil Nadu, India
3 Department of Uvea, Medical and Vision Research Foundations, Sankara Nethralaya, Chennai, Tamil Nadu, India

Correspondence Address:
Dr. Jyotirmay Biswas
Department of Uvea Sankara Nethralaya, 18, College Road, Nungambakkam, Chennai - 600 006, Tamil Nadu
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ijo.IJO_534_20

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A 65-year-old male presented with redness and pain associated with active necrotizing scleritis in the left eye. He was started on mycophenolate mofetil and oral corticosteroids, to which there was no response detected after 4 weeks. A rheumatology opinion was sought and he was started on tofacitinib, after which there was dramatic clinical improvement. Patients refractory to conventional immunosuppressive therapy can benefit from the new class of immunosuppressive agents, JAK/STAT kinase inhibitors.

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