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CASE REPORT
Year : 2020  |  Volume : 68  |  Issue : 9  |  Page : 2002-2003

Zoledronic acid induced unilateral anterior uveitis


1 Department of Ophthalmology, G.B. Pant Hospital, Andaman and Nicobar Islands Institute of Medical Sciences, Port Blair, Andaman and Nicobar, India
2 Department of Pharmacology, G.B. Pant Hospital, Andaman and Nicobar Islands Institute of Medical Sciences, Port Blair, Andaman and Nicobar, India

Correspondence Address:
Dr. Abhishek Onkar
Department of Ophthalmology, Andaman and Nicobar Islands Institute of Medical Sciences, Room No. 31, G.B. Pant Hospital, Atlanta Point, Port Blair - 744 104, Andaman and Nicobar
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ijo.IJO_1654_19

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Zoledronic acid is recommended for patients with osteoporosis. To report a case of unilateral anterior uveitis after zoledronate infusion. An osteoporotic patient presented with pain, visual loss, hyperemia, photophobia, and watering from the left eye after zoledronate infusion. Circumcorneal injection, keratic precipitates, cells, and flare suggested anterior uveitis. Her symptoms resolved completely after 20 days of prednisolone acetate with atropine eye drops. Uveitis is a rare complication of zoledronic acid with an unclear mechanism. Proinflammatory cytokines may play a role in pathogenesis. Zoledronic acid may be associated with rare but serious inflammatory ocular adverse drug reactions.


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