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Year : 2020  |  Volume : 68  |  Issue : 9  |  Page : 2037-2040

Correlation of vascular endothelial growth factor with the clinical regression of tubercular granuloma

1 Department of Vitreoretina services, Dr Shroff's Charity Eye Hospital, New Delhi, India
2 National Institute of Immunology, New Delhi, India

Correspondence Address:
Dr. Manisha Agarwal
Head of the Vitreo-Retina Services, Dr. Shroff's Charity Eye Hospital, 5072, Kedarnath Road, Daryaganj, New Delhi - 110 002
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ijo.IJO_1261_20

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Tubercular granulomas are a common manifestation of intraocular tuberculosis. These are said to be hypoxic granulomas with increased expression of vascular endothelial growth factor (VEGF). Management of these granulomas includes a combination of antitubercular therapy (ATT) and oral corticosteroids. We report a case of tubercular granuloma with exudative retinal detachment which was treated with weekly intravitreal anti-VEGF and antibiotic injections along with ATT and corticosteroids. The VEGF levels measured paralleled with the clinical regression of the granuloma.

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