CASE REPORT |
|
Year : 2020 | Volume
: 68
| Issue : 9 | Page : 2037-2040 |
|
Correlation of vascular endothelial growth factor with the clinical regression of tubercular granuloma
Manisha Agarwal1, Chanda Gupta1, K Varsha Mohan2, Pramod K Upadhyay2, Vivek Jha1
1 Department of Vitreoretina services, Dr Shroff's Charity Eye Hospital, New Delhi, India 2 National Institute of Immunology, New Delhi, India
Correspondence Address:
Dr. Manisha Agarwal Head of the Vitreo-Retina Services, Dr. Shroff's Charity Eye Hospital, 5072, Kedarnath Road, Daryaganj, New Delhi - 110 002 India
Source of Support: None, Conflict of Interest: None | Check |
DOI: 10.4103/ijo.IJO_1261_20
|
|
Tubercular granulomas are a common manifestation of intraocular tuberculosis. These are said to be hypoxic granulomas with increased expression of vascular endothelial growth factor (VEGF). Management of these granulomas includes a combination of antitubercular therapy (ATT) and oral corticosteroids. We report a case of tubercular granuloma with exudative retinal detachment which was treated with weekly intravitreal anti-VEGF and antibiotic injections along with ATT and corticosteroids. The VEGF levels measured paralleled with the clinical regression of the granuloma.
|
|
|
|
[FULL TEXT] [PDF]* |
|
|
|