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CASE REPORT
Year : 2020  |  Volume : 68  |  Issue : 9  |  Page : 2045-2047

Tubercular panophthalmitis in a patient with human immunodeficiency virus infection: Proven clinicopathologically and by molecular diagnostic tests


1 Department of Uvea, Sankara Nethralaya, Chennai, Tamil Nadu, India
2 Department of Vitreo-retina, Sankara Nethralaya, Chennai, Tamil Nadu, India

Correspondence Address:
Dr. Jyotirmay Biswas
Sankara Nethralaya, Sankara Nethralaya, 41, College Road, Nungambakkam, Chennai, Tamil Nadu
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ijo.IJO_1190_20

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Ocular tuberculosis (OTB) in patients with human immunodeficiency virus (HIV) commonly presents as choroidal tubercles or granuloma. We report a rare presentation of OTB with hypopyon granulomatous uveitis in a patient with HIV on highly active antiretroviral therapy (HAART). Aqueous humor polymerase chain reaction (PCR) was positive for Mycobacterium tuberculosis (MTB). Antitubercular therapy (ATT) was initiated despite which it progressed to scleral abscess and panophthalmitis. Enucleation with ball implantation was done. Histopathology revealed caseating granuloma with numerous acid-fast bacilli (AFB) and real-time PCR showed increased copies of MTB genome. After a full course of ATT, he had stable ocular and systemic condition at final follow-up.


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